R18
R18 is a peptide antagonists of 14-3-3, with a KD of 70-90 nM. R18 efficiently blocks the binding of 14-3-3 to the kinase Raf-1, a physiological ligand of 14-3-3, and effectively abolished the protective role of 14-3-3 against phosphatase-induced inactivation of Raf-1.
For research use only. We do not sell to patients.
- CAS No.: 211364-78-2
- Formula: C101H157N27O29S3
- Molecular Weight:2309.69
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 211364-78-2
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Molecular Weight 2309.69
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Formula C101H157N27O29S3
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Synonyms
PHCVPRDLSWLDLEANMCLP
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Sequence
Pro-His-Cys-Val-Pro-Arg-Asp-Leu-Ser-Trp-Leu-Asp-Leu-Glu-Ala-Asn-Met-Cys-Leu-Pro
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Sequence Shortening
PHCVPRDLSWLDLEANMCLP
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)