BRD4-IN-2
BRD4-IN-2 is a bromodomain BRD4 inhibitor with an IC50 value of 9.9 nM.
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- CAS No.: 2679925-55-2
- Formule: C43H48N8O11
- Masse moléculaire:852.89
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
16.9 nM
Compound: 2
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Protac activity at Halo-tagged CRBN/Nanoluc fused BRD4 in human HEK293 cells using nano-glo as substrate preincubated for 1 hr followed by substrate addition and measured after 3 min by NanoBRET assay
Protac activity at Halo-tagged CRBN/Nanoluc fused BRD4 in human HEK293 cells using nano-glo as substrate preincubated for 1 hr followed by substrate addition and measured after 3 min by NanoBRET assay
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[PMID: 36170570] |
Chemical Information
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CAS No. 2679925-55-2
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Masse moléculaire 852.89
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Formule C43H48N8O11
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SMILES
CNC(N1N=C(C2=C(C[C@@H]1C)C=C(C(OC)=C2)OC)C3=CC=C(C=C3)N4CCN(CC4)C(COCCOCC(NC5=C6C(N(C(C6=CC=C5)=O)C7CCC(NC7=O)=O)=O)=O)=O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BRD4-IN-2 Related Classifications
HY-141843 Related Classifications
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