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Cat. No.: HY-162591

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MR33317

MR33317 is an inhibitor of acetylcholinesterase with an IC₅₀ value of 41nM. MR33317 is also an agonist at brain 5-HT₄ receptors.

For research use only. We do not sell to patients.

Formula: C₂₂H₂₈ClN₃O₂
Molecular Weight:401.93

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

MR33317 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

MR33317 is an inhibitor of acetylcholinesterase with an IC₅₀ value of 41nM. MR33317 is also an agonist at brain 5-HT₄ receptors^[1].

IC₅₀ & Target

5-HT₄ Receptor

AChE

41 nM (IC₅₀)

All Cholinesterase (ChE) Isoforms :

AChE
BChE

All 5-HT Receptor Isoforms :

Chemical Information

Molecular Weight 401.93
Formula C₂₂H₂₈ClN₃O₂
SMILES

O=C(C1=CC(Cl)=C(N)C=C1OC)CCC2CCN(CC3=CC=CC(N)=C3)CC2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Joachim Neumann, et al. Studies on the mechanisms of action of MR33317. Naunyn Schmiedebergs Arch Pharmacol. 2024 Jun 10. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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MCE Japan Authorized Agent:

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MR33317

All Cholinesterase (ChE) Isoforms

All 5-HT Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

MR33317 Related Classifications

HY-162591 Related Classifications