SR10221
Based on 1 Customer Validation
SR10221, a noncovalent inverse agonist of PPARγ, represses downstream PPARγ target genes leading to growth inhibition in bladder cancer cell lines.
For research use only. We do not sell to patients.
- Purity: 98.96%
- CAS No.: 1415321-64-0
- Formula: C33H37ClN2O4
- Molecular Weight:561.11
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 1415321-64-0
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Appearance Solid
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Molecular Weight 561.11
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Formula C33H37ClN2O4
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Color White to off-white
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SMILES
C[C@@H](C1=CC=C(C=C1)C(C)(C)C)NC(C2=CC=C(C(C(C)=C3C)=C2)N3CC4=CC(O[C@@H](C)C(O)=O)=C(C=C4)Cl)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (222.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7822 mL | 8.9109 mL | 17.8218 mL | 44.5545 mL |
| 5 mM | 0.3564 mL | 1.7822 mL | 3.5644 mL | 8.9109 mL | |
| 10 mM | 0.1782 mL | 0.8911 mL | 1.7822 mL | 4.4555 mL | |
| 15 mM | 0.1188 mL | 0.5941 mL | 1.1881 mL | 2.9703 mL | |
| 20 mM | 0.0891 mL | 0.4455 mL | 0.8911 mL | 2.2277 mL | |
| 25 mM | 0.0713 mL | 0.3564 mL | 0.7129 mL | 1.7822 mL | |
| 30 mM | 0.0594 mL | 0.2970 mL | 0.5941 mL | 1.4852 mL | |
| 40 mM | 0.0446 mL | 0.2228 mL | 0.4455 mL | 1.1139 mL | |
| 50 mM | 0.0356 mL | 0.1782 mL | 0.3564 mL | 0.8911 mL | |
| 60 mM | 0.0297 mL | 0.1485 mL | 0.2970 mL | 0.7426 mL | |
| 80 mM | 0.0223 mL | 0.1114 mL | 0.2228 mL | 0.5569 mL | |
| 100 mM | 0.0178 mL | 0.0891 mL | 0.1782 mL | 0.4455 mL |