1,2-Hexanediol
Based on 1 Customer Validation
1,2-Hexanediol (Hexane-1,2-diol) is a broad-spectrum antibacterial agent. 1,2-Hexanediol exhibits bactericidal activity against Gram-positive and Gram-negative bacteria, as well as antifungal activity against fungal organisms. 1,2-Hexanediol disrupts the cytoplasmic membrane potential of bacteria. 1,2-Hexanediol can be used in research on bacterial and fungal infections, as well as cosmetic preservation.
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- No. CAS: 6920-22-5
- Fòrmula: C6H14O2
- Peso molecular:118.18
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Almacenamiento:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Actividad biológica
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Chemical Information
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- Referencias
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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Anti-Infection Compound Library
HY-L002
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Antifungal Compound Library
HY-L048
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HY-L183
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Actividad biológica
1,2-hexanediol (195-100000 ppm; 24-72 h) inhibits the growth of Escherichia coli NCTC 12923, Staphylococcus aureus NCTC 10788, Candida albicans NCPF 3179, and Aspergillus brasiliensis NCPF 2275, with MIC values of 12500, 25000, 12500, and 6250 ppm, respectively[1].
1,2-hexanediol (0-25000 ppm; 24-48 h) exerts synergistic inhibitory effects with Nicotinamide (HY-B0150) against Candida albicans NCPF 3179 and Aspergillus brasiliensis NCPF 2275, with FICI values of 0.375 and 0.3125, respectively; it exerts synergistic inhibitory effects with sodium cocoyl methyl taurate and sodium cocoyl alaninate against Escherichia coli NCTC 12923, with an FICI value of 0.375 for each combination; it also exerts a synergistic inhibitory effect with sodium C14-16 olefin sulfonate against Aspergillus brasiliensis NCPF 2275, with an FICI value of 0.375[1].
1,2-Hexanediol disrupts the cytoplasmic membrane potential of B. cereus ATCC 21772[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 6920-22-5
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Appearance Liquid (Density: 0.951 g/cm3)
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Peso molecular 118.18
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Fòrmula C6H14O2
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Color Colorless to light yellow
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SMILES
OCC(O)CCCC
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Synonyms
Hexane-1,2-diol
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Pureza y Documentación
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Ficha de datos (264 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Gim H, et al. Synergistic/antagonistic antimicrobial effects of cosmetic ingredients in combination with 1,2-hexanediol. J Microorg Control. 2024;29(4):133-142. [Content Brief]
[2]. Yogiara, et al. Food-grade antimicrobials potentiate the antibacterial activity of 1,2-hexanediol. Lett Appl Microbiol. 2015;60(5):431-439. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
1,2-Hexanediol Related Classifications
HY-W012880 Related Classifications
Powered by Bioz
- 1,2-Hexanediol
- 6920-22-5
- Hexane-1,2-diol
- Environmental Pollutants
- Fungal
- Bacterial
- bacterial cytoplasmic membrane potential
- niacinamide
- Staphylococcus aureus NCTC 10788
- Aspergillus brasiliensis NCPF 2275
- fungi
- Escherichia coli NCTC 12923
- Gram-positive bacteria
- Gram-negative bacteria
- Candida albicans NCPF 3179
- Bacillus cereus
- ntimicrobial agent
- Inhibitor
- inhibitor
- inhibit