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Referencia número: HY-N20636

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7α-Morroniside

7α-Morroniside is a STAT3 promoter inhibitor. 7α-Morroniside inhibits IL-6-induced STAT3 promoter activity in hepatocellular carcinoma cells. 7α-Morroniside can be used for the research of inflammation-related diseases.

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No. CAS: 61849-88-5
Fòrmula: C₁₇H₂₆O₁₁
Peso molecular:406.38

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Please store the product under the recommended conditions in the Certificate of Analysis.

7α-Morroniside Chemical Structure

No. CAS: 61849-88-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Descripciòn

IC₅₀ & Target^[1]

STAT3

Ver todos los productos específicos de isoformas STAT :

In Vitro

7α-Morroniside (Compound 22) (7 μM; 1 h pre-incubation + 6 h co-incubation with IL-6) potently inhibits IL-6-induced STAT3 promoter activity in HepG2 cells, with an IC₅₀ of 7 μM, and shows no cytotoxicity at effective concentrations^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 61849-88-5
Peso molecular 406.38
Fòrmula C₁₇H₂₆O₁₁
SMILES

COC(C1=CO[C@H]([C@@]2([H])[C@]1([H])C[C@H](O[C@H]2C)O)O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)=O
Structure Classification
- Phenylpropanoids
- Lignans
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Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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Instrucciones de manejo (2659 KB)

Referencias

[1]. Ye XS, et al.. Cornusides A-O, Bioactive Iridoid Glucoside Dimers from the Fruit of Cornus officinalis. Journal of natural products. 2017 Dec 22;80(12):3103-3111. [Content Brief]

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1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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7α-Morroniside

Ver todos los productos específicos de isoformas STAT

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