BET-IN-2
BET-IN-2 is a BET inhibitor with an IC50 of 52 nM for BRD4-BD1.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2104688-91-5
- Fòrmula: C23H29N3O
- Peso molecular:363.50
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Protocolo
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
Descripciòn
IC50 & Target
[1]|
BRD4 BD1 52 nM (IC50) |
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MM1.S | IC50 |
0.016 μM
Compound: 54
|
Antiproliferative activity against human MM1S cells after 72 hrs by CCK8 assay
Antiproliferative activity against human MM1S cells after 72 hrs by CCK8 assay
|
[PMID: 28586718] |
Chemical Information
-
No. CAS 2104688-91-5
-
Peso molecular 363.50
-
Fòrmula C23H29N3O
-
SMILES
CC1=C([C@H](C)NC2=CC(N(C3CC3)[C@H](C)C(N4C)=O)=C4C=C2)C=CC(C)=C1
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BET-IN-2 Related Classifications
HY-102044 Related Classifications
Powered by Bioz