Atalaphyllidine
Atalaphyllidine is a natural product. Atalaphyllidine can be isolated from the stem bark of Glycosmis chlorosperma. Atalaphyllidine inhibits DYRK1A kinase activity with an IC50 of 2.2 μM. Atalaphyllidine can be used in the research of neurodegenerative diseases.
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- No. CAS: 57959-88-3
- Fòrmula: C18H15NO4
- Peso molecular:309.32
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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DYRK1A 2.2 μM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
6.98 μM
Compound: 9
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Antiproliferative activity against human A549 cells after 3 days by alamar blue assay
Antiproliferative activity against human A549 cells after 3 days by alamar blue assay
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[PMID: 10217715] |
Atalaphyllidine (30 min) inhibits DYRK1A kinase activity with an IC50 of 2.2 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 57959-88-3
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Peso molecular 309.32
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Fòrmula C18H15NO4
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SMILES
O=C1C2=C(NC3=C4C=CC(C)(C)OC4=CC(O)=C13)C(O)=CC=C2
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Atalaphyllidine Related Classifications
HY-N17356 Related Classifications
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