country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Referencia número: HY-50692

Copy Link Print Information

CAY10734

Name: CAY10734
Brand: MedChemExpress
SKU: HY-50692
Price: 122.00 USD
Availability: InStock
Rating: 5 (1 reviews)

CAY10734 is the agonist for sphingosine-1-phosphate receptor 1 (S1P1) with an IC₅₀ of 1.3 nM. CAY10734 promotes the recirculation of peripheral blood lymphocytes, and is a potential immunosuppressant.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 635701-59-6
Fòrmula: C₂₃H₂₅N₃O₃
Peso molecular:391.46

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

CAY10734 Chemical Structure

No. CAS: 635701-59-6

Tamaño

Precio

Stock

Cantidad

Amount: USD 0.00

* Seleccione Cantidad antes de agregar artículos.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- Cellular Effect
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

Ver todos los productos específicos de isoformas LPL Receptor :

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	IC₅₀	0.6 nM Compound: 26	Concentration required for displacement of [33P]-labeled S1P from human sphingosine 1-phosphate receptor 1 expressed in CHO cells Concentration required for displacement of [33P]-labeled S1P from human sphingosine 1-phosphate receptor 1 expressed in CHO cells	[PMID: 16190743]
CHO	IC₅₀	1 nM Compound: 26	Concentration required for displacement of [33P]-labeled S1P from human sphingosine 1-phosphate receptor 5 expressed in CHO cells Concentration required for displacement of [33P]-labeled S1P from human sphingosine 1-phosphate receptor 5 expressed in CHO cells	[PMID: 16190743]
CHO	IC₅₀	70 nM Compound: 26	Concentration required for displacement of [33P]-labeled S1P from human sphingosine 1-phosphate receptor 4 expressed in CHO cells Concentration required for displacement of [33P]-labeled S1P from human sphingosine 1-phosphate receptor 4 expressed in CHO cells	[PMID: 16190743]
CHO	IC₅₀	>10000 nM Compound: 26	Concentration required for displacement of [33P]-labeled S1P from human sphingosine 1-phosphate receptor 2 expressed in CHO cells Concentration required for displacement of [33P]-labeled S1P from human sphingosine 1-phosphate receptor 2 expressed in CHO cells	[PMID: 16190743]
CHO	IC₅₀	12 μM Compound: 26	Concentration required for displacement of [33P]-labeled S1P from human sphingosine 1-phosphate receptor 3 expressed in CHO cells Concentration required for displacement of [33P]-labeled S1P from human sphingosine 1-phosphate receptor 3 expressed in CHO cells	[PMID: 16190743]
CHO	IC₅₀	>10 μM Compound: 5	Displacement of [33P]S1P from human S1P2 receptor expressed in CHO cells Displacement of [33P]S1P from human S1P2 receptor expressed in CHO cells	[PMID: 16621543]
CHO	IC₅₀	0.6 nM Compound: 5	Displacement of [33P]S1P from human S1P1 receptor expressed in CHO cells Displacement of [33P]S1P from human S1P1 receptor expressed in CHO cells	[PMID: 16621543]
CHO	IC₅₀	1 nM Compound: 5	Displacement of [33P]S1P from human S1P5 receptor expressed in CHO cells Displacement of [33P]S1P from human S1P5 receptor expressed in CHO cells	[PMID: 16621543]
CHO	IC₅₀	70 nM Compound: 5	Displacement of [33P]S1P from human S1P4 receptor expressed in CHO cells Displacement of [33P]S1P from human S1P4 receptor expressed in CHO cells	[PMID: 16621543]
CHO	IC₅₀	12 μM Compound: 5	Displacement of [33P]S1P from human S1P3 receptor expressed in CHO cells Displacement of [33P]S1P from human S1P3 receptor expressed in CHO cells	[PMID: 16621543]
CHO	IC₅₀	0.6 nM Compound: C	Displacement of [33P]S1P from human S1P1R expressed in CHO cell membranes Displacement of [33P]S1P from human S1P1R expressed in CHO cell membranes	[PMID: 24900286]
CHO	IC₅₀	12 nM Compound: C	Displacement of [33P]S1P from human S1P3R expressed in CHO cell membranes Displacement of [33P]S1P from human S1P3R expressed in CHO cell membranes	[PMID: 24900286]

Chemical Information

No. CAS 635701-59-6
Peso molecular 391.46
Fòrmula C₂₃H₂₅N₃O₃
SMILES

O=C(O)C1CN(C1)CC2=CC=C(C=C2)C3=NOC(C4=CC=C(CC(C)C)C=C4)=N3
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Li Z, et al., Discovery of potent 3,5-diphenyl-1,2,4-oxadiazole sphingosine-1-phosphate-1 (S1P1) receptor agonists with exceptional selectivity against S1P2 and S1P3. J Med Chem. 2005 Oct 6;48(20):6169-73. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Obtener un presupuesto En stock

Other size

Obtener un presupuesto