Copy Link Print Information

Cevostamab

(Synonyms: BFCR 4350A; RG 6160; RO 7187797)
Revisión del cliente

Based on 1 Customer Validation

Cevostamab (BFCR4350A; RG6160; RO7187797) is a humanized IgG1-based BsAb that targets membrane-proximal extracellular domain of FcRH5 on multiple myeloma (MM) cells as well as CD3 on T cells. Moreover, Cevostamab facilitates efficient synapse formation, improves killing activity of T cells against MM tumor cells.

Para uso exclusivo en investigación. No vendemos a pacientes.

  • Pureza: ≥99%
  • No. CAS: 2249888-53-5
  • Peso molecular:146.19 kDa
  • Almacenamiento:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Cevostamab
  • Experimental Validation Results for Cevostamab
  • Experimental Validation Results for Cevostamab
  • Experimental Validation Results for Cevostamab
  • Cevostamab Chemical Structure
    Cevostamab Chemical Structure
No. CAS: 2249888-53-5
Tamaño
Precio
Stock
Cantidad
Amount: USD 0.00
Please select quantity
or
or

* Seleccione Cantidad antes de agregar artículos.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Cevostamab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
  • Actividad biológica
  • Chemical Information
  • Pureza y Documentación
  • Referencias
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products
Keywords
MOQ
Minimum order quantity
100 mg

Obtener un presupuesto En stock

Other size
Obtener un presupuesto
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Inicie sesiòn
Registrar
Sign in to MedChemExpress
Registrar una cuenta nueva

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Loaded Cevostamab on AHC2 biosensor, can bind FcRH5/FcRL5 Protein, Human (HEK293, His, HY-P700302) with an affinity constant of 1.605E-11 M as determined in BLI assay.

  • 1/16

    Flow cytometric analysis of 1X106 HepG2 cells labeling FcRH5 with Cevostamab (HY-P99601, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control.

  • 1/16

    Loaded Cevostamab on AHC2 biosensor, can bind CD3 epsilon Protein, Human (HEK293, His, HY-P70506) with an affinity constant of 3.265E-11 M as determined in BLI assay.

  • Cevostamab Chemical Structure
    1/16
  • Cevostamab
  • Loaded Cevostamab on AHC2 biosensor, can bind FcRH5/FcRL5 Protein, Human (HEK293, His, HY-P700302) with an affinity constant of 1.605E-11 M as determined in BLI assay.
  • Flow cytometric analysis of 1X106 HepG2 cells labeling FcRH5 with Cevostamab (HY-P99601, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control.
  • Loaded Cevostamab on AHC2 biosensor, can bind CD3 epsilon Protein, Human (HEK293, His, HY-P70506) with an affinity constant of 3.265E-11 M as determined in BLI assay.