D228
Based on 1 Customer Validation
D228 is an orally active antiinflammatory agent. D228 reduces ConA induced T lymphocyte cell proliferation (IC50: 42.85 μM) and LPS induced B lymphocyte cell proliferation (IC50: 3.15 μM). D228 is effective against inflammatory bowel disease (IBD). D228 alleviates the DSS (HY-116282C)-induced inflammation response in the IBD model by downregulating the MyD88/TRAF6/p38 signaling.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.77%
- No. CAS: 2676188-98-8
- Fòrmula: C22H28O12
- Peso molecular:484.45
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
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Immunology/Inflammation Compound Library
HY-L007
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Kinase Inhibitor Library
HY-L009
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MAPK Compound Library
HY-L010
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Reprogramming Compound Library
HY-L039
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Oxygen Sensing Compound Library
HY-L045
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Pyroptosis Compound Library
HY-L059
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Orally Active Compound Library
HY-L061
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Anti-Lung Cancer Compound Library
HY-L075
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Anti-Cancer Metabolism Compound Library
HY-L083
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Neurodegenerative Disease-related Compound Library
HY-L086
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Anti-Obesity Compound Library
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Angiogenesis-Related Compound Library
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Antidepressant Compound Library
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Anti-Prostate Cancer Compound Library
HY-L124
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Anti-Pulmonary Fibrosis Compound Library
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Pain-Related Compound Library
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Serine/Threonine Kinase Inhibitor Library
HY-L164
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Anti-Ovarian Cancer Compound Library
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Multi-Target Compound Library
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Protein Kinase Compound Library
HY-L196
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Cell Proliferation Compound Library
HY-L201
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High-Throughput Bioactive Compound Library
HY-L205
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Anti-Rheumatic Arthritis Compound Library
HY-L210
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Posttranslational Modification Library
HY-L226
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Lactylation Compound Library
HY-L249
Actividad biológica
Chemical Information
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No. CAS 2676188-98-8
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Appearance Solid
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Peso molecular 484.45
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Fòrmula C22H28O12
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Color White to off-white
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SMILES
CC1=C(C(/C(O1)=C(C)\C)=O)O[C@H]2[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](COC(C)=O)O2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : 50 mg/mL (103.21 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (278 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0642 mL | 10.3210 mL | 20.6420 mL | 51.6049 mL |
| 5 mM | 0.4128 mL | 2.0642 mL | 4.1284 mL | 10.3210 mL | |
| 10 mM | 0.2064 mL | 1.0321 mL | 2.0642 mL | 5.1605 mL | |
| 15 mM | 0.1376 mL | 0.6881 mL | 1.3761 mL | 3.4403 mL | |
| 20 mM | 0.1032 mL | 0.5160 mL | 1.0321 mL | 2.5802 mL | |
| 25 mM | 0.0826 mL | 0.4128 mL | 0.8257 mL | 2.0642 mL | |
| 30 mM | 0.0688 mL | 0.3440 mL | 0.6881 mL | 1.7202 mL | |
| 40 mM | 0.0516 mL | 0.2580 mL | 0.5160 mL | 1.2901 mL | |
| 50 mM | 0.0413 mL | 0.2064 mL | 0.4128 mL | 1.0321 mL | |
| 60 mM | 0.0344 mL | 0.1720 mL | 0.3440 mL | 0.8601 mL | |
| 80 mM | 0.0258 mL | 0.1290 mL | 0.2580 mL | 0.6451 mL | |
| 100 mM | 0.0206 mL | 0.1032 mL | 0.2064 mL | 0.5160 mL |
D228 Related Classifications
HY-164670 Related Classifications
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