Disulfamide
Disulfamide, an orally active diuretic, is a carbonic anhydrase inhibitor with the IC50 value of 0.07 μM. Disulfamide leads to diuresis by inhibiting carbonic anhydrase and preventing the reabsorption of sodium and bicarbonate in the proximal tubule.
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- No. CAS: 671-88-5
- Fòrmula: C7H9ClN2O4S2
- Peso molecular:284.74
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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HY-B0553
MethazolamideCarbonic Anhydrase Inhibitor -
HY-108316
SultiameCarbonic Anhydrase Inhibitor -
HY-B0483
TioxoloneCarbonic Anhydrase Inhibitor -
HY-147662
hCAIX-IN-5hCAIX Inhibitor -
HY-B0553R
Methazolamide (Standard)Carbonic Anhydrase Inhibitor -
HY-B0483R
Tioxolone (Standard)Carbonic Anhydrase Inhibitor -
HY-108316R
Sultiame (Standard)Carbonic Anhydrase Inhibitor
Actividad biológica
Descripciòn
IC50 & Target
IC50: 0.07 μM (carbonic anhydrase)[1]
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Wistar rats weighing between 200-300 g[2]
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Dosage:200 mg/kg
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Administration:Intraperitoneal injection; once
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Result:Resulted in elevated blood sugar levels from an initial blood glucose concentration of 143.1 mg/100 mL to a one hour later final concentration of 194.6 mg/100 mL, an increase of 36%.
Chemical Information
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No. CAS 671-88-5
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Peso molecular 284.74
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Fòrmula C7H9ClN2O4S2
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SMILES
O=S(C1=C(C)C=C(Cl)C(S(=O)(N)=O)=C1)(N)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Disulfamide Related Classifications
HY-137364 Related Classifications
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