DPC 961
DPC 961 (DMP 961) is a non-nucleoside reverse transcriptase inhibitor (NNRTI). DPC 961 is a potent and specific inhibitor of HIV-1 reverse transcriptase, which inhibits the activity of HIV-1 reverse transcriptase in a non-competitive manner, thereby preventing viral replication. DPC 961 can be used for research on AIDS.
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- No. CAS: 214287-88-4
- Fòrmula: C14H10ClF3N2O
- Peso molecular:314.69
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Chemical Information
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No. CAS 214287-88-4
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Peso molecular 314.69
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Fòrmula C14H10ClF3N2O
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SMILES
FC(F)(F)[C@@]1(C2=CC(Cl)=CC=C2NC(N1)=O)C#CC3CC3
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Synonyms
(S)-DPC 961; DMP 961
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Mutlib A, et al. Characterization of Novel Glutathione Adducts of a Non-Nucleoside Reverse Transcriptase Inhibitor,(S)-6-Chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-3, 4-dihydro-2 (1 H)-quinazolinone (DPC 961), in Rats. Possible Formation of an Oxirene Metabolic Intermediate from a Disubstituted Alkyne[J]. Chemical research in toxicology, 2000, 13(8): 775-784. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)