DU172
DU172 is a ligand for the adenosine A1 receptor (Adenosine A1 Receptor), with an IC50 of 24.9 nM against A1AR and an IC50 of 0.42 μM against A2AAR.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 321907-03-3
- Fòrmula: C24H30FN5O5S
- Peso molecular:519.59
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Ver todos los productos específicos de isoformas Adenosine Receptor
More
Actividad biológica
DU172 (Compound 23a) potently binds to the A1 adenosine receptor on the cell membrane of DDT1 MF-2, with an IC50 of 24.9 nM for inhibiting [3H]DPCPX binding[2].
DU172 binds to the A2A adenosine receptor on the membrane of PC-12 cells, with an IC50 of 0.42 μM[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
No. CAS 321907-03-3
-
Peso molecular 519.59
-
Fòrmula C24H30FN5O5S
-
SMILES
O=C(NCCCN1C(=O)N(C(=O)C=2NC(=NC21)C3CCCCC3)CCC)C4=CC=C(C=C4)S(=O)(=O)F
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Glukhova A, et al. Structure of the Adenosine A1 Receptor Reveals the Basis for Subtype Selectivity. Cell. 2017;168(5):867-877.e13. [Content Brief]
[2]. Beauglehole AR, et al. Fluorosulfonyl-substituted xanthines as selective irreversible antagonists for the A(1)-adenosine receptor. J Med Chem. 2000;43(26):4973-4980. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DU172 Related Classifications
HY-165509 Related Classifications
Powered by Bioz