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Referencia número: HY-W744272

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Estetrol-d₃

Estetrol-d₃ is the deuterium labeled Estetrol (HY-15731). Estetrol, an orally active estrogen synthesized exclusively during pregnancy by the human fetal liver, is a selective nuclear?estrogen receptor?modulator. Estetrol binds?ERα?as well as?ERβ?(with a fourfold lower affinity). Estetrol increases?eNOS?expression/activity and NO synthesis in endothelial cells. Estetrol exerts estrogenic actions on the endometrium or the central nervous system but presents antagonistic effects on the breast. Estetrol can be used in contraception and menopausal hormone research.

Para uso exclusivo en investigación. No vendemos a pacientes.

Fòrmula: C₁₈H₂₁D₃O₄
Peso molecular:307.40

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Estetrol-d₃ Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- In Vitro
- Aplicación
Chemical Information
Pureza y Documentación
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

Ver todos los productos específicos de isoformas NO Synthase :

Ver todos los productos específicos de isoformas Endogenous Metabolite :

Ver todos los productos específicos de isoformas Estrogen Receptor/ERR :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Aplicación

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 15183-37-6
Peso molecular 307.40
Fòrmula C₁₈H₂₁D₃O₄
SMILES

O[C@@]1([C@]2(CC[C@]3([C@@]([H])(CCC4=C(C(O)=C(C=C43)[2H])[2H])[C@@]2([C@H]([C@H]1O)O)[H])[H])C)[2H]
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.