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United States

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Referencia número: HY-186186

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FD236

FD236, an eIF4A inhibitor, is the payload of DL149 (HY-183253).

Para uso exclusivo en investigación. No vendemos a pacientes.

Fòrmula: C₂₉H₃₁NO₈
Peso molecular:521.56

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

FD236 Chemical Structure

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Actividad biológica
- Descripciòn
- In Vivo
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
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Actividad biológica

Descripciòn

FD236, an eIF4A inhibitor, is the payload of DL149 (HY-183253).

Ver todos los productos específicos de isoformas ADC Payloads :

In Vivo

ADCs carying payloads FD236 is tolerated up to 30 mg/kg in non-tumor bearing BALB/c mice.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Peso molecular 521.56
Fòrmula C₂₉H₃₁NO₈
SMILES

O=C([C@@H]1[C@@H](C2=CC=CC=C2)[C@@](OC3=C4C(OC)=CC(OC)=C3)(C5=CC=C(OC)C=C5)[C@@]4(O)[C@@H]1O)NCCO
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Petersen M, et al. Design and evaluation of mRNA translation inhibitors for use as antibody drug conjugate payloads.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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100 mg

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