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Referencia número: HY-169184

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GDC-9918

GDC-9918 (compund GDC-9918) is a Janus kinase inhibitor.

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No. CAS: 2570375-06-1
Fòrmula: C₂₀H₁₈F₂N₆O₅S
Peso molecular:492.46

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

GDC-9918 Chemical Structure

No. CAS: 2570375-06-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Descripciòn

GDC-9918 (compund GDC-9918) is a Janus kinase inhibitor^[1].

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Janus^[1]

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Chemical Information

No. CAS 2570375-06-1
Peso molecular 492.46
Fòrmula C₂₀H₁₈F₂N₆O₅S
SMILES

O=C(C1=C2N=CC=CN2N=C1)NC3=CN(C)N=C3C4=CC(S(=O)(CCO)=O)=CC=C4OC(F)F
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Dalton D M, et al. Development of a Robust Pd-Catalyzed C–S Coupling for the Synthesis of Janus Kinase Inhibitor GDC-9918[J]. Organic Process Research & Development, 2024, 28(10): 3858-3870.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

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Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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GDC-9918

Ver todos los productos específicos de isoformas JAK

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IC50 & Target

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GDC-9918 Related Classifications

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