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IBI-363

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Based on 1 Customer Validation

IBI-363 is a PD-1/IL-2 bispecific antibody with functions of blocking the PD-1/PD-L1 pathway and activating the IL-2 pathway. The IL-2 arm of IBI-363 retains affinity for IL-2Rα but attenuates binding ability to IL-2Rβ and IL-2Rγ to reduce toxicity. The PD-1 binding arm of IBI-363 enables PD-1 blockade and selective delivery of IL-2. IBI-363 can be used in cancer research, such as non-small cell lung cancer.

Para uso exclusivo en investigación. No vendemos a pacientes.

  • Pureza: 99.92%
  • Peso molecular:112.48 kDa
  • Almacenamiento:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for IBI-363
  • Experimental Validation Results for IBI-363
  • IBI-363 Chemical Structure
    IBI-363 Chemical Structure
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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IBI-363 Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    PD-1/IL-2 α-bias bispecific antibody

  • 1/16

    Immobilized PD-1 Protein, Human (HEK293, HY-P7396) can bind IBI-363. The ED50 for this effect is 4.714 ng/mL.

  • IBI-363 Chemical Structure
    1/16
  • IBI-363
  • Immobilized PD-1 Protein, Human (HEK293, HY-P7396) can bind IBI-363. The ED50 for this effect is 4.714 ng/mL.
  • PD-1/IL-2 α-bias bispecific antibody