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Referencia número: HY-206897

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Insecticidal agent 34

Insecticidal agent 34 is an orally active insecticide. Insecticidal agent 34 inhibits voltage-gated sodium channel and blocks acetylcholine release. Insecticidal agent 34 induces ataxia, paralysis, curling, tremors/convulsions and progressive death in lepidopteran larvae, inhibits neural activity in the central nervous system, and blocks nerve firing in larval stretch receptor preparations. Insecticidal agent 34 can be used for insecticidal research.

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No. CAS: 183992-66-7
Fòrmula: C₂₉H₂₈F₆N₂O₅
Peso molecular:598.53

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Insecticidal agent 34 Chemical Structure

No. CAS: 183992-66-7

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In Vitro

Insecticidal agent 34 (Compound 4) potently inhibits veratridine-induced acetylcholine release from synaptosomes of the house cricket (Acheta domesticus), with a pIC₅₀ of 6.56^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Insecticidal agent 34 (feed mixing; continuous administration; 10 days) exhibits delayed in vivo toxicity against late 2nd-instar Heliothis virescens larvae. After 10 days of feed exposure, its lethal pLC₅₀ is 5.7 and growth-inhibitory pI₅₀ is 6.56^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

late second instar larvae^[1]
Dosage:

Diet incorporation
Administration:

continuous; 10 days
Result:

Exhibited slow-onset toxicity with an LC₅₀ corresponding to a pLC₅₀ of 5.7 after 10 days of diet exposure.
Achieved an IC₅₀ for growth inhibition corresponding to a pI₅₀ of 6.56 after 10 days of diet exposure.

Chemical Information

No. CAS 183992-66-7
Peso molecular 598.53
Fòrmula C₂₉H₂₈F₆N₂O₅
SMILES

O=C(NC1=CC=C(CN2CCC(C(C3=CC=C(C=C3)OC(F)(F)F)(C4=CC=C(C=C4)OC(F)(F)F)O)CC2)C=C1)OC
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. J.R Bloomquist, et al. Toxicity and mode of action of benzhydrolpiperidines and related compounds in insects. Pesticide Biochemistry and Physiology
Volume 73, Issue 1, May 2002, Pages 18-26.

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Insecticidal agent 34

Ver todos los productos específicos de isoformas Sodium Channel

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Insecticidal agent 34 Related Classifications

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