Kansuinine E
Kansuinine E is a plant-derived nitric oxide inhibitor (IC50=6.3 μM). Kansuinine E belongs to jatrophane-type diterpenoids and is isolated from the roots of E. kansui.
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- No. CAS: 672945-84-5
- Fòrmula: C41H47NO14
- Peso molecular:777.81
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
IC50: 6.3 μM (nitric oxide)[1].
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| NIH3T3 | ED50 |
>50 μg/mL
Compound: 5, kansuinin E
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Survival effect on NGF-dependent mouse NIH/3T3 cells expressing TrkB assessed as cell viability after 2 days by MTT assay
Survival effect on NGF-dependent mouse NIH/3T3 cells expressing TrkB assessed as cell viability after 2 days by MTT assay
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[PMID: 15387657] |
| NIH3T3 | ED50 |
0.23 μg/mL
Compound: 5, kansuinin E
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Survival effect on NGF-dependent mouse NIH/3T3 cells expressing TrkA assessed as cell viability after 2 days by MTT assay
Survival effect on NGF-dependent mouse NIH/3T3 cells expressing TrkA assessed as cell viability after 2 days by MTT assay
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[PMID: 15387657] |
Chemical Information
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No. CAS 672945-84-5
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Peso molecular 777.81
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Fòrmula C41H47NO14
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SMILES
C[C@H]1C[C@@]2(OC(C)=O)[C@@H]([C@@H](OC(C)=O)C([C@H](OC(C)=O)[C@@H](OC(C3=CC=CC=C3)=O)[C@@H](OC(C4=CN=CC=C4)=O)C(C)(C)[C@@H]5[C@H]([C@@H](C)C2=O)O5)=C)[C@H]1OC(C)=O
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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