KHK-6
KHK-6 is an inhibitor for serine/threonine kinase hematopoietic progenitor kinase 1 (HPK 1) with an IC50 of 20 nM. KHK-6 enhances CD3/CD28-induced cytokine production, enhances CD69, CD25 and HLA-DR markers on CD4+ and CD8+ T cells, and enhances T cell-mediated killing activity of SKOV3 and A549 cells.
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- Fòrmula: C23H23ClN4O4S
- Peso molecular:486.97
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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HPK1 20 nM (IC50) |
Chemical Information
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Peso molecular 486.97
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Fòrmula C23H23ClN4O4S
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SMILES
CC(S(=O)(C1=C(C=CC=C1)NC2=C(C=NC(NC3=CC=C4C(OC(C)(C4=C3)C)=O)=N2)Cl)=O)C
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)