LS24-16
LS24-16 is a carbonic anhydrase (CA) IX enzyme inhibitor (Ki ≤ 1.6 nM versus human CA IX; Kd = 0.40 nM). LS24-16 inhibits carbon dioxide hydration by binding to the catalytic zinc site and displacing the zinc-bound water with its deprotonated sulfamate amino group. LS24-16 competes with fluorescent CA IX probes for binding to CA IX on hypoxic cells and remains stable under the tested stress conditions. LS24-16 can be used for solid tumor research.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2352790-85-1
- Fòrmula: C13H13NO4S
- Peso molecular:279.31
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
Descripciòn
IC50 & Target
[1]|
hCA IX 0.40 nM (Kd) |
CA VII 6.1 nM (Kd) |
CA XIII 6.2 nM (Kd) |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
No. CAS 2352790-85-1
-
Peso molecular 279.31
-
Fòrmula C13H13NO4S
-
SMILES
NS(OC1=CC=CC=C1OCC2=CC=CC=C2)(=O)=O
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LS24-16 Related Classifications
HY-190902 Related Classifications
Powered by Bioz