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Referencia número: HY-117031

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m-PEG8-MS

Name: m-PEG8-MS
Brand: MedChemExpress
SKU: HY-117031
Price: 76.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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m-PEG8-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG8-MS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Para uso exclusivo en investigación. No vendemos a pacientes.

Pureza : 99.98%
No. CAS: 1059588-19-0
Fòrmula: C₁₈H₃₈O₁₁S
Peso molecular:462.55

Almacenamiento:

Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

m-PEG8-MS Chemical Structure

No. CAS: 1059588-19-0

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Descripciòn

m-PEG8-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG8-MS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)^[1].

IC₅₀ & Target

^[1]

Cleavable Linker

PEGs

Ver todos los productos específicos de isoformas ADC Linkers :

Ver todos los productos específicos de isoformas PROTAC Linkers :

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 1059588-19-0
Appearance Liquid
Peso molecular 462.55
Fòrmula C₁₈H₃₈O₁₁S
Color Colorless to light yellow
SMILES

CS(OCCOCCOCCOCCOCCOCCOCCOCCOC)(=O)=O
Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Pure form	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (261 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Sanxing Sun, et al. Triazolotriazine derivatives as a2a receptor antagonists. WO2020002969A1.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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m-PEG8-MS

Ver todos los productos específicos de isoformas ADC Linkers

Ver todos los productos específicos de isoformas PROTAC Linkers

Actividad biológica

Descripciòn

IC50 & Target

In Vitro

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