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Referencia número: HY-171467

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MRS7799

Name: MRS7799
Brand: MedChemExpress
SKU: HY-171467
Availability: PreOrder

(Synonyms: DPTN)

MRS7799 is a selective A 3 Adenosine Receptor antagonist agsinst human, mouse, and rat A3AR with K_ds of 0.55, 3.74 and 2.80 nM, respectively. MRS7799 can be used in the study of neurodegeneration, cancer, ischemia of the heart and brain, autoimmune inflammatory diseases.

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No. CAS: 224040-19-1
Fòrmula: C₂₂H₁₈N₄OS
Peso molecular:386.47

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

MRS7799 Chemical Structure

No. CAS: 224040-19-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

Ver todos los productos específicos de isoformas Adenosine Receptor :

Chemical Information

No. CAS 224040-19-1
Peso molecular 386.47
Fòrmula C₂₂H₁₈N₄OS
SMILES

O=C(C1=CC=CN=C1)NC2=NC(C3=CC(C)=CC(C)=C3)=C(C4=CC=NC=C4)S2
Synonyms

DPTN
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocolo

All Animals and Diseases

Neurotoxicity Study
This protocol assesses in vitro neurotoxicity by combining neuronal viability, mitochondrial/metabolic activity, neurite outgrowth, and optional neuronal network function readouts. Calcein-AM or resazurin/PrestoBlue readouts estimate viable or metabolically active cells; βIII-tubulin immunofluorescence detects neuronal morphology and neurite networks; TMRE detects mitochondrial membrane potential; and MEA recordings detect functional changes in neuronal network activity.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Suresh RR, et al. Selective A3 Adenosine Receptor Antagonist Radioligand for Human and Rodent Species. ACS Med Chem Lett. 2022 Mar 2;13(4):623-631. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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