Picrasidine J
Picrasidine J is a selective inhibitor targeting the KLK-10 protease and the ERK signaling pathway. Picrasidine J inhibits epithelial-mesenchymal transition (EMT) by upregulating E-Cadherin and ZO-1 and downregulating β-catenin and Snail, while simultaneously reducing KLK-10 expression and inhibiting ERK phosphorylation, thereby exhibiting significant anti-migratory and anti-invasive activity. Picrasidine J can inhibit the metastasis of head and neck squamous cell carcinoma (HNSCC) and is primarily used in anti-metastasis research for head and neck tumors.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 100234-62-6
- Fòrmula: C14H14N2O2
- Peso molecular:242.27
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Actividad biológica
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KLK10 |
E-cadherin (CDH1) |
Chemical Information
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No. CAS 100234-62-6
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Peso molecular 242.27
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Fòrmula C14H14N2O2
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SMILES
OC1=CC=CC2=C1NC3=C2C(OC)=CN=C3CC
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Picrasidine J Related Classifications
HY-N16719 Related Classifications
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