Platencin
Platencin is a natural, broad spectrum Gram-positive antibiotic isolated from S. platensis. Platencin inhibits β-ketoacyl-ACP synthases II and III (FabF and FabH, respectively) with IC50s of 1.95 and 3.91 μg/ml, respectively.
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- No. CAS: 869898-86-2
- Fòrmula: C24H27NO6
- Peso molecular:425.47
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
>100 μg/mL
Compound: Platencin
|
Cytotoxicity against human HeLa cells by MTT assay
Cytotoxicity against human HeLa cells by MTT assay
|
[PMID: 17456595] |
| HeLa | IC50 |
86 μM
Compound: 2
|
Cytotoxicity against human HeLa cells by MTT assay
Cytotoxicity against human HeLa cells by MTT assay
|
[PMID: 20299229] |
Chemical Information
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No. CAS 869898-86-2
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Peso molecular 425.47
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Fòrmula C24H27NO6
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SMILES
O=C1C=C[C@]2(CC3)CC([C@@]3(C[C@]2([C@@]1(CCC(NC4=C(C(C(O)=O)=CC=C4O)O)=O)C)[H])[H])=C
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)