PyP-1
PyP-1 is a highly selective and potent PDE10 inhibitor. PyP-1 has a strong inhibitory effect on human PDE10A2 enzyme (Ki = 0.32 nM). PyP-1 can improve cognitive behavior. PyP-1 commonly used in research on conditions such as schizophrenia and cognitive impairment.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1370527-16-4
- Fòrmula: C20H21N7O
- Peso molecular:375.43
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
IC50 & Target
[1]|
PDE10A2 0.32 nM (Ki) |
Chemical Information
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No. CAS 1370527-16-4
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Peso molecular 375.43
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Fòrmula C20H21N7O
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SMILES
CN1N=CC(CNC2=CC(OC[C@@H]3[C@@H](C4=NC=CC=C4)C3)=NC5=CC=NN25)=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)