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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
225 Results for "
hepg2-cell
" in MedChemExpress (MCE) Product Catalog:
Products (225)
225 Results for "hepg2-cell" in MCE Product Catalog:
Referencia número: HY-N8679
No. CAS: 27503-33-9
Target:
Category:
Human Gut Microbiota Metabolites Flavonoids Citrus limon (L.) Burm. F. Rutaceae Plants Endogenous metabolite Disease Research Fields Cancer
Target:
Referencia número: HY-N7605
No. CAS: 2146088-12-0
Category:
Triterpenes Terpenoids Cucurbitaceae Metabolic Disease Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants Disease Research Fields
Target:
Referencia número: HY-170992
Target:
Áreas de investigación:
Autophagy agonist-1 (compound 22) is an Autophagy agonist. Autophagy agonist-1 exhibits significant anticancer activity against HepG2 cells and normal cells with IC50s of 8.8 μM and > 50 μM. Autophagy agonist-1 induces G1/S phase cell cycle arrest and inhibits CDK4 and CyclinD1 expression while upregulating P21. Autophagy agonist-1 promotes the accumulation of autophagosomes and the proteins LC3 and PINK1, enhancing autophagy and mitophagy in HepG2 cells .
Referencia número: HY-142101
No. CAS: 214283-58-6
Target:
Referencia número: HY-146084
No. CAS: 2476490-18-1
Target:
Áreas de investigación:
PCSK9 modulator-3 is a PCSK9 modulator that reduces the secretion level of PCSK9 protein in HepG2 cells. PCSK9 modulator-3 exhibits metabolic stability in liver microsomes of mice and rats. PCSK9 modulator-3 can be used for the study of hyperlipidemia .
Referencia número: HY-N12158
No. CAS: 71627-22-0
Target:
Referencia número: HY-N8361
No. CAS: 233279-39-5
Referencia número: HY-176416
No. CAS: 1174836-23-7
Target:
Áreas de investigación:
USP7-IN-17 (compound M15) is a potent USP7 inhibitor. USP7-IN-17 inhibits HepG2 cell activity with an IC50 of 4.38 μM .
Referencia número: HY-126644
No. CAS: 122548-04-3
Referencia número: HY-175208A
Target:
Áreas de investigación:
MST3-IN-1 TFA (Compound LD-1) is a selective and orally active MST3 inhibitor, with an IC50 of 122.4 nM. MST3-IN-1 TFA shows antiproliferative activity against HepG2 cell. MST3-IN-1 TFA effectively induces Apoptosis in HepG2 cells, and halts the cell cycle at the G2/M transition. MST3-IN-1 TFA significantly suppressed tumor growth in HepG2 xenograft mice. MST3-IN-1 TFA can be used for the study of liver cancer .
Referencia número: HY-N0316R
No. CAS: 55481-88-4
Referencia número: HY-N8466
No. CAS: 143236-02-6
Target:
Referencia número: HY-N10063
Target:
Referencia número: HY-173140
Anticancer agent 268 (Compound 4k) is a potential anti-tumor agent. Anticancer agent 268 exhibits anti-proliferative effects against HepG2 cells, with an IC50 of 6.08 μM. Anticancer agent 268 can induce apoptosis and inhibit colony formation and migration of HepG2 cells .
Referencia número: HY-N9010
No. CAS: 1528745-88-1
Category:
Target:
Referencia número: HY-N11433
No. CAS: 1950581-97-1
Target:
Category:
Target:
Referencia número: HY-N10207
No. CAS: 1338332-27-6
Category:
Infection Natural Products Microorganisms Marine natural products Disease Research Fields Marine microorganism
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
