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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2438 Results for "
decrease
" in MedChemExpress (MCE) Product Catalog:
Products (2438)
2438 Results for "decrease" in MCE Product Catalog:
Target:
Áreas de investigación:
Infection Neurological Disease Inflammation/Immunology Cancer
Allopurinol (Standard) is the analytical standard of Allopurinol. This product is intended for research and analytical applications. Allopurinol is a potent and orally active xanthine oxidase inhibitor with an IC50 value of 0.2-50 μM. Allopurinol can be used in the research of hyperuricemia and gout. Allopurinol decreases the expression of HIF-1α and HIF-2α protein. Allopurinol shows anti-depressant and anti-nociception activity. Anti-leishmanial effect .
Referencia número: HY-B0523AR
No. CAS: 58579-51-4
Synonyms: BL4162A (Standard)
Áreas de investigación:
Anagrelide (hydrochloride) (Standard) is the analytical standard of Anagrelide (hydrochloride). This product is intended for research and analytical applications. Anagrelide hydrochloride (BL4162A) is a potent inhibitor of phosphodiesterase type III (PDE3) (IC50=36 nM). Anagrelide hydrochloride, an imidazoquinazoline derivative, acts as an inhibitor of platelet aggregation. Anagrelide hydrochloride inhibits bone marrow megakaryocytopoiesis. Anagrelide hydrochloride decreases gastrointestinal stromal tumor (GIST) cell proliferation and promotes their apoptosis in vitro. Anagrelide hydrochloride is a platelet-lowering agent and plays in the antithrombopoietic action .
Referencia número: HY-B0859S1
No. CAS: 352431-14-2
Referencia número: HY-E70787
AMPK is an αβγ heterotrimeric serinethreonine kinase activated by decreasing concentrations of adenosine triphosphate (ATP) and increasing AMP concentrations. AMPK α1β1γ1 Recombinant Human Active Protein Kinase is an ortholog of AMPK. AMPK α1β1γ1 Recombinant Human Active Protein Kinase is obtained by co-expressing AMPKα1, AMPKβ1, and AMPKγ1 proteins .
Category:
Alkaloids Plant Corydalis yanhusuo W. T. Wang Extract Quinoline Alkaloids Papaveraceae Extract
Target:
Referencia número: HY-N22057
No. CAS: 186892-52-4
Target:
Referencia número: HY-N2342R
No. CAS: 37064-30-5
Synonyms: PCC1 (Standard)
Category:
Plant Flavonoids Rosaceae Extract Phenols Polyphenols Biflavones Crataegus pinnatifida Bge. Extract
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Category:
Solanum tuberosum Linn. Extract Alkaloids Piperidine Alkaloids Plant Pyrrole Alkaloids Microorganism Disease Research Fields Cancer Solanaceae Extract
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Referencia número: HY-N7860
No. CAS: 93772-82-8
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Referencia número: HY-P2637
No. CAS: 94162-23-9
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Áreas de investigación:
Renin inhibitory peptide, statine is an inhibitor of Renin. Renin inhibitory peptide, statine inhibits the plasma renin activity of human plasma renin, porcine renin, and sodium-depleted conscious dogs. Renin inhibitory peptide, statine reduces the mean arterial pressure of sodium-depleted conscious dogs, induces a sustained, dose-dependent decrease in blood pressure, and triggers a maximum hypotensive response. Renin inhibitory peptide, statine can be used in hypertension-related research .
Referencia número: HY-P4146
No. CAS: 2805997-46-8
Synonyms: BI 456906
Target:
Áreas de investigación:
Survodutide (BI 456906) is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .
Referencia número: HY-P4146B
Synonyms: BI 456906 sodium
Target:
Áreas de investigación:
Survodutide (BI 456906) sodium is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide sodium, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide sodium has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .
Referencia número: HY-P990012
No. CAS: 2744320-12-3
Synonyms: EBI-031
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Áreas de investigación:
Referencia número: HY-P990213
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Referencia número: HY-P990264
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Referencia número: HY-P990635
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Áreas de investigación:
NGM-120 is a fully humanized IgG1 monoclonal antibody targeting GFRAL, which functions by blocking the GDF15-GFRAL axis. NGM-120 reduces serum GDF15 levels, increases body weight, expands central memory and proliferative CD8 + T cell populations, and decreases immunosuppressive and naive regulatory T cell populations. NGM-120 can be used for research on advanced prostate cancer .
Referencia número: HY-P991365
Target:
Áreas de investigación:
Referencia número: HY-P991609
No. CAS: 561063-60-3
Referencia número: HY-W013274S
Áreas de investigación:
CPTH2-d4 is the deuterated-labeled CPTH2 (HY-W013274). CPTH2 is a potent histone acetyltransferase (HAT) inhibitor. CPTH2 selectively inhibits the acetylation of histone H3 by Gcn5. CPTH2 induces apoptosis and decreases the invasiveness of a clear cell renal carcinoma (ccRCC) cell line through the inhibition of acetyltransferase p300 (KAT3B) .
Referencia número: HY-W014130R
No. CAS: 155-84-0
Synonyms: Ac-Arg-OH (Standard)
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
