63 Results for "

Urease

" in MedChemExpress (MCE) Product Catalog:
Products (63)

63 Results for "Urease" in MCE Product Catalog:

  • Categories Recommended:
    More
2
2 Cited Publications
Referencia número: HY-N3101
No. CAS: 22384-63-0
Pedalitin is a tyrosinase and α-glucosidase inhibitor with IC50 values of 0.28 mM and 0.29 mM, respectively, and can be isolated and extracted from Rabdosia serra. Pedalitin is a xanthine oxidase (Xanthine Oxidase) (IC50 = 3.7 µM) and myeloperoxidase (MPO) (IC50 = 3.8 nM) inhibitor. Pedalitin ameliorates NAFLD by downregulating the EGFR/IRS1/AKT1/FOXO1 signaling pathway and related inflammatory and lipid metabolism factors. Pedalitin reduces the risk of urinary tract infection and stones by inhibiting the expression of the urease UreC gene in Proteus mirabilis. Pedalitin also exhibits antifungal activity, with a MIC of 3.9 mg/L against Cryptococcus neoformans. Pedalitin can be used for research on non-alcoholic fatty liver disease, chronic kidney disease, kidney stones, cryptococcosis, and abdominal pain .
loading...
    loading...
1
1 Cited Publications
Referencia número: HY-B1235
No. CAS: 546-88-3
Synonyms: N-Hydroxyacetamide
Acetohydroxamic acid is the inhibitor for bacterial and plant urease that can be used for chronic urinary tract infections. Acetohydroxamic acid selectively inhibits arachidonic acid 5-lipoxygenase that is useful in the research of asthma. Acetohydroxamic acid inhibits the formation of advanced glycation end products, and reduces oxidative stress and inflammatory responses. Acetohydroxamic acid exhibits antiviral activity against HIV .
loading...
    loading...
1
1 Cited Publications
Referencia número: HY-P2767
No. CAS: 9002-13-5
Target:  

Bacterial

Áreas de investigación:  

Others

Urease, Jack bean is derived from jack bean and Catalyzes hydrolysis of urea to carbon dioxide and ammonia. Urease, Jack bean is useful in the determination of urea in body fluids.
loading...
    loading...
Referencia número: HY-W015551
No. CAS: 3913-81-3
Synonyms: (E)-Dec-2-enal
trans-2-Decenal ((E)-Dec-2-enal) acts as a urease inhibitor and antibacterial agent against Helicobacter pylori, with an IC50 of 9.484 μg/mL against Helicobacter pylori urease. trans-2-Decenal reduces the urease activity of Helicobacter pylori, and possesses antibacterial, bactericidal, anti-biofilm and anti-migratory activities. It alters the morphology of Helicobacter pylori, induces bacterial rupture, inhibits biofilm formation, reduces the number of mature biofilms and impairs the migratory capacity of Helicobacter pylori. trans-2-Decenal disrupts the cell wall integrity of Phytophthora capsici, damages membrane integrity and permeability, triggers intracellular reactive oxygen species (ROS) accumulation, decreases glutathione levels and disrupts the mitochondrial membrane potential of Phytophthora capsici. trans-2-Decenal is applicable to studies related to Helicobacter pylori and plant diseases induced by and Phytophthora capsici .
loading...
    loading...
Referencia número: HY-100956
No. CAS: 70788-28-2
Pureza:  ≥92.0%
Target:  

Bacterial Urease

Áreas de investigación:  

Infection Metabolic Disease

Flurofamide is an effective bacterial urease inhibitor and antibacterial agent. Flurofamide inhibits urease and partially inhibits the chemotactic activity of Helicobacter pylori strain CPY3401. Flurofamide inhibits the growth of Ureaplasma urealyticum. Flurofamide reduces blood ammonia. Flurofamide can be used in the research of infectious urinary stones .
loading...
    loading...
Referencia número: HY-N2224
No. CAS: 22255-13-6
Guaijaverin is a urease inhibitor with an IC50 of 120 μM. Guaijaverin shows antioxidant and anti-Streptococcus mutans activities .
loading...
    loading...
Referencia número: HY-107199
No. CAS: 94317-64-3
Pureza:  99.76%
Synonyms: NBPT
Áreas de investigación:  

Others

N-Butylthiophosphoric triamide (NBPT) is a potent urease inhibitor. Butylthiophosphoric triamide inhibits nitrification and reduces the conversion of urea to NH3 gas .
loading...
    loading...
Referencia número: HY-E70003
No. CAS: 9001-46-1
Áreas de investigación:  

Endocrinology

Glutamate dehydrogenase is an enzyme in both prokaryotes and eukaryotic mitochondria. Glutamate dehydrogenase can be used for the enzymatic determination of ammonia, alpha-ketoglutaric acid, L-glutamate and urease .
loading...
    loading...
Referencia número: HY-P5290
No. CAS: 2213408-17-2
Áreas de investigación:  

Cancer

HYNIC-PSMA is a ligand for molecular imaging of tumors. Hynic-psma consists of two components: HYNIC (6-hydrazinonicotinamide) and PSMA (Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules, such as 188Re-HYNIC-PSMA. PSMA is a membrane antigen that is specifically expressed on the surface of prostate cancer cells. HYNIC-PSMA can be used in prostate cancer research . HYNIC-PSMA can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
loading...
    loading...
Referencia número: HY-W013014
No. CAS: 2758-18-1
3-Methyl-2-cyclopenten-1-one is an α,β-unsaturated carbonyl compound and an endogenous metabolite. 3-Methyl-2-cyclopenten-1-one exhibits weak glutathione (GSH) reactivity and urease (Urease) inhibitory activity. 3-Methyl-2-cyclopenten-1-one can be used in research on peptic ulcers and colorectal cancer .
loading...
    loading...
Referencia número: HY-W001857
No. CAS: 7377-03-9
Synonyms: N-Hydroxyoctanamide; Caprylhydroxamic acid
Áreas de investigación:  

Infection

Octanohydroxamic acid (N-Hydroxyoctanamide) is a Urease inhibitor. Octanohydroxamic acid acts as a chelating agent that binds to metal cations, thereby assisting in the purification of tin ore. Octanohydroxamic acid is also used as a preservative. Octanohydroxamic acid can be used in research on Escherichia coli infection .
loading...
    loading...
Referencia número: HY-W000932
No. CAS: 4426-47-5
Target:  

Urease Phosphatase

Áreas de investigación:  

Endocrinology

Butylboronic acid is a competitive soybean urease inhibitor with an IC50 of 2.9 mM and a Ki of 1.5 mM .
loading...
    loading...
Referencia número: HY-P5292A
No. CAS: 2375849-11-7
Áreas de investigación:  

Cancer

HYNIC-iPSMA TFA is a PSMA-targeted ligand for tumor molecular imaging, with a Ki value of 3.11 nM. HYNIC-iPSMA TFA consists of two components: HYNIC (6-hydrazinonicotinamide) and iPSMA (Inhibitor of Prostate-Specific Membrane Antigen). HYNIC serves as a chelating moiety to link radionuclides to the targeting molecule; iPSMA is a specific inhibitor that targets Prostate-Specific Membrane Antigen (PSMA). 68Ga-labeled iPSMA is used for prostate cancer detection via PET imaging, while the further developed 99mTc-EDDA/HYNIC-iPSMA TFA exhibits excellent specificity and sensitivity. HYNIC-iPSMA TFA can be used for the synthesis and research of radionuclide-conjugated drugs (RDC) .
loading...
    loading...
Referencia número: HY-B1235R
No. CAS: 546-88-3
Synonyms: N-Hydroxyacetamide (Standard)
Áreas de investigación:  

Infection Inflammation/Immunology

Acetohydroxamic acid (Standard) is the analytical standard of Acetohydroxamic acid. This product is intended for research and analytical applications. Acetohydroxamic acid is the inhibitor for bacterial and plant urease that can be used for chronic urinary tract infections. Acetohydroxamic acid selectively inhibits arachidonic acid 5-lipoxygenase that is useful in the research of asthma. Acetohydroxamic acid inhibits the formation of advanced glycation end products, and reduces oxidative stress and inflammatory responses. Acetohydroxamic acid exhibits antiviral activity against HIV .
loading...
    loading...
Referencia número: HY-W090317
No. CAS: 137-18-8
Synonyms: DMBQ; 2,5-Dimethyl-p-quinone; Phlorone
Target:  

Urease

Áreas de investigación:  

Others

2,5-Dimethyl-1,4-benzoquinone is a jack bean urease (HY-P2767) inhibitor (IC50: 0.98 μM). 2,5-Dimethyl-1,4-benzoquinone can be used in the study of soil urease activity in agriculture .
loading...
    loading...
Referencia número: HY-P5292
No. CAS: 2192215-74-8
Áreas de investigación:  

Cancer

HYNIC-iPSMA is a PSMA-targeted ligand for tumor molecular imaging, with a Ki value of 3.11 nM. HYNIC-iPSMA consists of two components: HYNIC (6-hydrazinonicotinamide) and iPSMA (Inhibitor of Prostate-Specific Membrane Antigen). HYNIC acts as a chelating moiety to link radionuclides to the targeting molecule; iPSMA is a specific inhibitor that targets Prostate-Specific Membrane Antigen (PSMA). 68Ga-labeled iPSMA is used for prostate cancer detection via PET imaging, while the further developed 99mTc-EDDA/HYNIC-iPSMA TFA exhibits excellent specificity and sensitivity. HYNIC-iPSMA can be used for the synthesis and research of radionuclide-conjugated drugs (RDC) .
loading...
    loading...
Referencia número: HY-147787
No. CAS: 2543651-72-3
Target:  

Bacterial Urease

Áreas de investigación:  

Infection

Urease-IN-3 (Compound L12) is a potent inhibitor of Urease with an IC50 of 1.449 μM. Urease-IN-3 is a flavonoid analogue compound .
loading...
    loading...
Referencia número: HY-161998
No. CAS: 1203704-26-0
Target:  

Bacterial Urease

Áreas de investigación:  

Others

Urease-IN-16 (compound 4e) is a urease inhibitor, with an IC50 value of 132 μmol/L. Urease-IN-16 can coordinate with the nickel atom through the oxygen atoms of carbonyl or boronic acid groups. Urease-IN-16 shows great potential as an additive in the development of efficient fertilizers and medical applications .
loading...
    loading...
Referencia número: HY-W012824
No. CAS: 2835-99-6
Áreas de investigación:  

Others

4-Amino-m-cresol inhibits soil urease activity .
loading...
    loading...
Referencia número: HY-107792
No. CAS: 38274-54-3
Target:  

Bacterial

Áreas de investigación:  

Infection

Benurestat is an orally active urease inhibitor. Benurestat can be used for infected ureolysis research .
loading...
    loading...