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Referencia número: HY-106515

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Tebuquine

(Synonyms: WR228258)

Tebuquine (WR228258), a 4-aminoquinoline, is a potent antimalarial agent. Tebuquine is active against the Chloroquine (HY-17589A) sensitive HB3 strain and the Chloroquine resistant K1 strain of Plasmodium falciparum with IC₅₀s of 0.9 nM and 20.8 nM, respectively.

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No. CAS: 74129-03-6
Fòrmula: C₂₆H₂₅Cl₂N₃O
Peso molecular:466.40

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Tebuquine Chemical Structure

No. CAS: 74129-03-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Actividad biológica

Descripciòn

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Cellular Effect

Cell Line	Type	Value	Description	References
J774	IC₅₀	1.8 μg/mL Compound: tebuquine	Toxicity against murine J774 macrophage cells Toxicity against murine J774 macrophage cells	[PMID: 17266295]

Chemical Information

No. CAS 74129-03-6
Peso molecular 466.40
Fòrmula C₂₆H₂₅Cl₂N₃O
SMILES

ClC1=CC=C(C2=CC(NC3=C4C=CC(Cl)=CC4=NC=C3)=CC(CNC(C)(C)C)=C2O)C=C1
Synonyms

WR228258
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. P M O'Neill, et al. Synthesis, antimalarial activity, and molecular modeling of tebuquine analogues. J Med Chem. 1997 Feb 14;40(4):437-48. [Content Brief]

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Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Tebuquine

Ver todos los productos específicos de isoformas Parasite

Actividad biológica

Chemical Information

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Referencias

Calculators

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Tebuquine Related Classifications

HY-106515 Related Classifications