Amd1 - S-adenosylmethionine decarboxylase 1 Gene

Also Known as Amd-1; SAMDC; SAMDC 1; AdoMetDC; adoMetDC1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11702

Summary

Enables adenosylmethionine decarboxylase activity. Acts upstream of or within in utero embryonic development; spermidine biosynthetic process; and spermine biosynthetic process. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; central nervous system; cranium; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human AMD1 (adenosylmethionine decarboxylase 1). [provided by Alliance of Genome Resources, Apr 2022]

Amd1 Products (1)

mRNA Protein Name
NM_009665.5 NP_033795.1 S-adenosylmethionine decarboxylase proenzyme 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15102471 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

S-adenosylmethionine decarboxylase proenzyme 1

  • adoMetDC 1

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-109561 Pegaptanib sodium Inhibitor 90.51% Unkown

Clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Phase
HY-P3252A Pegcetacoplan acetate Inhibitor 99.92% Phase 3
HY-19720A Emixustat hydrochloride Inhibitor 99.29% Phase 3
HY-N0679S Retinyl acetate-d3 / Phase 3
HY-15492 AG-13958 Inhibitor 99.69% Phase 2
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99629 Galegenimab Inhibitor 99.91% Phase 2

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-19720 Emixustat 98.00% Yes
HY-132126 SPHINX Inhibitor 99.87% Unkown
HY-RS09498 NPR2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-15492A AG-13958 (mono(hydrochloride)) Inhibitor / Unkown
HY-RS00644 AMD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18124 Amd1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24598 Amd1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Amd1 NCBI NCBI:262