Dyrk1b - dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b Gene

Also Known as Mirk

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13549

Summary

Predicted to enable protein serine/threonine kinase activity and transcription coactivator activity. Acts upstream of or within myoblast fusion. Predicted to be located in chromosome and nucleoplasm. Predicted to be active in nucleus. Is expressed in olfactory epithelium. Human ortholog(s) of this gene implicated in abdominal obesity-metabolic syndrome 3. Orthologous to human DYRK1B (dual specificity tyrosine phosphorylation regulated kinase 1B). [provided by Alliance of Genome Resources, Apr 2022]

Dyrk1b Products (3)

mRNA Protein Name
NM_001037957.3 NP_001033046.1 dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform p69
NM_001271370.1 NP_001258299.1 dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform p75
NM_010092.2 NP_034222.1 dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform p65

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within myoblast fusion IMP
IMP: Inferred from mutant phenotype
12902328 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dual specificity tyrosine-phosphorylation-regulated kinase 1B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (27)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-12277 AZ191 Inhibitor 99.98% Unkown
HY-115470 CLK-IN-T3 Inhibitor 99.78% Unkown
HY-108476 INDY Inhibitor 99.32% Unkown
HY-112296 T025 99.64% Unkown
HY-111380 EHT 1610 Inhibitor 98.93% Unkown
HY-12838 RO5454948 Inhibitor 99.53% Unkown
HY-155723 Leucettinib-92 Inhibitor 98.54% Unkown
HY-146221 Dyrk1A-IN-5 Inhibitor 98.06% Unkown
HY-117391 AZ-Dyrk1B-33 Inhibitor 99.78% Unkown
HY-111379 EHT 5372 Inhibitor 98.12% Unkown
HY-128758A DYRKs-IN-1 hydrochloride Inhibitor 98.29% Unkown
HY-128758 DYRKs-IN-1 Inhibitor / Unkown
HY-402805 DYRK2-IN-2 Inhibitor / Unkown
HY-402805A DYRK2-IN-2 hydrochloride Inhibitor / Unkown
HY-128759 DYRKs-IN-2 Inhibitor / Unkown
HY-144614 JH-XVII-10 / Unkown
HY-144617 JH-XIV-68-3 Inhibitor / Unkown
HY-146337 Dyrk1A/B-IN-1 Inhibitor / Unkown
HY-175477 UNC9750 Inhibitor / Unkown
HY-177416 MU1787 Inhibitor / Unkown
HY-RS04097 DYRK1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-108475 ProINDY Inhibitor / Unkown
HY-119607 DYRKi Inhibitor / Unkown
HY-181085 RD0448 Inhibitor / Unkown
HY-77324S 4-(Trifluoromethyl)aniline-d4 Inhibitor 99.23% Unkown
HY-RS17311 Dyrk1b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23766 Dyrk1b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dyrk1b NCBI NCBI:9149