2. Gene
  3. Il15 - interleukin 15 Gene

Il15 - interleukin 15 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as IL-15

Gene ID: 16168 | Gene type: protein coding

About Il15

Chromosome 8: 83,058,261-83,129,851 reverse strand.GRCm39:CM001001.3

This gene has 10 transcripts (splice variants), 128 orthologues and is associated with 42 phenotypes. Broad expression in heart adult (RPKM 5.2), duodenum adult (RPKM 3.3) and 24 other tissues.

Summary

This gene encodes a a pleiotropic cytokine of the interleukin family of proteins that plays important roles in the innate and adaptive cell homeostasis, as well as peripheral immune function. The encoded protein undergoes proteolytic processing to generate a mature cytokine that stimulates the proliferation of natural killer cells. The transgenic mice overexpressing the encoded protein exhibit an increase in the number of memory CD8+ T cells in a naive state and enhanced protection against Bacterial infections. Mice lacking the encoded protein exhibit impaired protection against a strain of attenuated Mycobacterium. [provided by RefSeq, Aug 2016]

Il15 Products(2)

mRNA Protein Name
NM_001254747.2 NP_001241676.1 interleukin-15 preproprotein
NM_008357.3 NP_032383.1 interleukin-15 preproprotein

Il15 Protein Structure

IL15

IL15: cl03560 (32 - 153)

  • 0
  • 100
  • 162 a.a.
Protein Preferred Names Protein Names

interleukin-15

Recombinant Il15 Proteins

Cat. No. Product Name Accession Purity
HY-P78558 IL-15R alpha & IL-15 Protein, Mouse (HEK293, His) Q60819 (M1-K205) & P48346 (M1-S162) ≥95%
HY-P78719 IL-15 Protein, Mouse (HEK293, Fc) P48346 (N49-S162) ≥95%
HY-P78859 IL-15 Protein, Mouse (Biotinylated, HEK293, Fc-Avi) P48346 (N49-S162) ≥95%
HY-P79152 IL-15 Protein, Mouse P48346 (N49-S162) ≥95%
HY-P700193AF Animal-Free IL-15 Protein, Mouse (His) P48346 (N49-S162) ≥95%

Related Agents

Clinical Phase
Inhibitory Antibodies (3)
Cat. No. Product Name Effect
Purity Phase
HY-P99850 Depemokimab Inhibitor / Phase 3
HY-P99661 Inbakicept Activator 98.95% Phase 2
HY-P99410 Ordesekimab Inhibitor 95.00% Phase 2
Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15898 Y-320 99.74% Unkown
HY-102049 IL-15-IN-1 Inhibitor 99.42% Unkown
HY-Y0493 HODHBt 99.93% Unkown
HY-153050 JAK-IN-24 Inhibitor 96.35% Unkown
HY-RS06690 IL15 Human Pre-designed siRNA Set A / Unkown
HY-RS06691 Il15 Mouse Pre-designed siRNA Set A / Unkown
HY-RS06692 Il15 Rat Pre-designed siRNA Set A / Unkown
HY-RS06693 IL15RA Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il15 NCBI NCBI:3600
Susscrofa domestica Il15 NCBI
Macaca mulatta Il15 NCBI NCBI:699616