Usp7 - ubiquitin specific peptidase 7 Gene

Also Known as Hausp; 2210010O09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 252870

Summary

Enables cysteine-type endopeptidase activity and thiol-dependent Deubiquitinase. Involved in histone H2B conserved C-terminal lysine deubiquitination; regulation of circadian rhythm; and regulation of protein stability. Located in XY body; cytoplasm; and nucleus. Is expressed in embryo and trophectoderm. Orthologous to human USP7 (ubiquitin specific peptidase 7). [provided by Alliance of Genome Resources, Apr 2022]

Usp7 Products (1)

mRNA Protein Name
NM_001003918.2 NP_001003918.2 ubiquitin carboxyl-terminal hydrolase 7

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cysteine-type deubiquitinase activity IDA
IDA: Inferred from direct assay
21268065 MGI
enables cysteine-type deubiquitinase activity IMP
IMP: Inferred from mutant phenotype
27863226 MGI
enables cysteine-type endopeptidase activity IMP
IMP: Inferred from mutant phenotype
21268065 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
18716620 MGI
Biological Process GO Annotation Evidence References Source
involved in protein deubiquitination IDA
IDA: Inferred from direct assay
21268065 MGI
involved in regulation of circadian rhythm IMP
IMP: Inferred from mutant phenotype
27123980 MGI
involved in regulation of protein stability IMP
IMP: Inferred from mutant phenotype
27123980 MGI
involved in transcription elongation-coupled chromatin remodeling IMP
IMP: Inferred from mutant phenotype
27863226 MGI
Cellular Component GO Annotation Evidence References Source
located in XY body IDA
IDA: Inferred from direct assay
25634095 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
12093161 MGI
located in nucleus IDA
IDA: Inferred from direct assay
12093161 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase 7

  • deubiquitinating enzyme 7

  • herpesvirus-associated ubiquitin-specific protease

  • mHAUSP

  • ubiquitin specific protease 7

  • ubiquitin thioesterase 7

  • ubiquitin thiolesterase 7

  • ubiquitin-specific-processing protease 7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (23)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-13453 BAY 11-7082 Inhibitor 99.98% Unkown
HY-158039 YCH2823 Inhibitor 99.87% Unkown
HY-101666 HBX 41108 Inhibitor 98.91% Unkown
HY-136910 USP7-797 Inhibitor 99.09% Unkown
HY-148369 U7D-1 Degrader 99.68% Unkown
HY-175360 USP7 Ligand-Linker Conjugates 1 Inhibitor 99.92% Unkown
HY-183282 LC-U7-44 Inhibitor / Unkown
HY-162794 YCH3124 Inhibitor / Unkown
HY-175359 USP7-IN-19 Inhibitor / Unkown
HY-180826 USP7 ligand-2 Ligand / Unkown
HY-153942 USP7-IN-12 Inhibitor / Unkown
HY-183689 OAT-4828 Inhibitor / Unkown
HY-159175 XM-U-14 Degrader / Unkown
HY-175358 PROTAC USP7 Degrader-1 Degrader / Unkown
HY-175793 USP7 ligand-1 Ligand / Unkown
HY-183078 P6620 Inhibitor / Unkown
HY-159964 USP7-IN-16 Inhibitor / Unkown
HY-49319 USP7-IN-14 Inhibitor / Unkown
HY-180793 PROTAC USP7 Degrader-2 Degrader / Unkown
HY-168121 USP7-IN-15 Inhibitor / Unkown
HY-124739 HBX 28258 Inhibitor / Unkown
HY-164544 USP7-055 Inhibitor / Unkown
HY-183942 USP7-IN-20 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Usp7 NCBI NCBI:7874