Mpg - N-methylpurine-DNA glycosylase Gene

Also Known as Aag; APNG; Mid1; 9830006D05

Species: Mus musculus

Gene Type: protein coding
Gene ID: 268395

Summary

Enables alkylbase DNA N-glycosylase activity. Acts upstream of or within base-excision repair. Predicted to be located in cytosol and nucleoplasm. Is expressed in several structures, including early conceptus; gonad; hemolymphoid system gland; musculature; and placenta. Orthologous to human MPG (N-methylpurine DNA glycosylase). [provided by Alliance of Genome Resources, Apr 2022]

Mpg Products (1)

mRNA Protein Name
NM_010822.3 NP_034952.2 DNA-3-methyladenine glycosylase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Verweise Source
enables alkylbase DNA N-glycosylase activity IDA
IDA: Inferred from direct assay
8435858 MGI
enables alkylbase DNA N-glycosylase activity IMP
IMP: Inferred from mutant phenotype
9371767 MGI
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within base-excision repair IMP
IMP: Inferred from mutant phenotype
9371767 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA-3-methyladenine glycosylase

  • 3-alkyladenine DNA glycosylase

  • 3-methyladenine DNA glycosidase

  • 3-methyladenine DNA glycosylase

  • ADPG

  • alkylpurine-DNA-N-glycosylase

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Art. -Nr. Produktname Wirkung
Reinheit Rare Diseases
HY-B0084 Dienogest Agonist 99.93% Unkown

Clinical Phase

Bioactive Molecules (5)
Art. -Nr. Produktname Wirkung
Reinheit Phase
HY-139364 mPGES1-IN-4 Inhibitor / Phase 4
HY-147416 Vipoglanstat Inhibitor 99.86% Phase 2
HY-139589 Zaloglanstat 98.50% Phase 1
HY-105005 Crisdesalazine 98.92% Phase 1
HY-122064 FR20 Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (49)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-Y0958 Methoxyamine hydrochloride 98.0% Unkown
HY-118119 CAY10526 99.12% Unkown
HY-108259 HQL-79 Inhibitor 99.89% Unkown
HY-13283 MF63 Inhibitor 99.55% Unkown
HY-10439 HPGDS inhibitor 1 Inhibitor 99.42% Unkown
HY-100800 TACA Agonist 99.33% Unkown
HY-W749694 Cannflavin B Inhibitor 98.36% Unkown
HY-P4076 MPG peptides, Pβ 98.26% Unkown
HY-118282 mPGES1-IN-7 Inhibitor 99.78% Unkown
HY-162387 UK4b Inhibitor 96.17% Unkown
HY-179041 SZ0232 99.25% Unkown
HY-149202 UT-11 Inhibitor 98.25% Unkown
HY-111140 YS121 99.74% Unkown
HY-125415 PF-4693627 Inhibitor 99.63% Unkown
HY-125975 1-Naphthyl 3,5-dinitrobenzoate Inhibitor 99.49% Unkown
HY-156612 Friluglanstat Inhibitor / Unkown
HY-176977 Exatecan-mpGly-Asn-Asn-(βAla) 96.25% Unkown
HY-19622 PF-9184 Inhibitor 98.10% Unkown
HY-169858 Prostaglandin E2 Inhibitor 3 Inhibitor 99.2% Unkown
HY-100864 mPGES1-IN-3 Inhibitor / Unkown
HY-111097 AF3442 Inhibitor / Unkown
HY-117008 CAY10589 Inhibitor / Unkown
HY-118506 BRP-7 Inhibitor / Unkown
HY-126898 5-LO/mPGES1-IN-1 Inhibitor 99.00% Unkown
HY-139365 mPGES1-IN-5 Inhibitor / Unkown
HY-144237 BRP-201 / Unkown
HY-144238 mPGES1-IN-6 / Unkown
HY-162166 COX-2/15-LOX/mPGES1-IN-1 Inhibitor / Unkown
HY-163736 mPGES-1/5-LOX-IN-1 Inhibitor / Unkown
HY-169430 AGU654 Inhibitor / Unkown
HY-170610 mPGES-1/sEH-IN-1 Inhibitor / Unkown
HY-171237 mPGES1-IN-9 Inhibitor / Unkown
HY-172713 DSPE-PEG1000-MPG / Unkown
HY-172714 DSPE-PEG2000-MPG / Unkown
HY-172714A DSPE-PEG3400-MPG / Unkown
HY-172715 DSPE-PEG5000-MPG / Unkown
HY-178505 mPGES1-IN-10 Inhibitor / Unkown
HY-178794 AGU661 Inhibitor / Unkown
HY-182647 LY3023703 Inhibitor / Unkown
HY-B0084S4 Dienogest-13C,15N,d4 Agonist / Unkown
HY-N9814 Shanciol B Inhibitor / Unkown
HY-P1566 MPG, HIV related / Unkown
HY-P4076A MPG-Cys / Unkown
HY-RS08611 MPG Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-118184 AF3485 Inhibitor / Unkown
HY-13475 mPGES1-IN-8 Inhibitor / Unkown
HY-164358 α-Gracinoic acid Inhibitor / Unkown
HY-RS18738 Mpg Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25225 Mpg Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mpg NCBI NCBI:4350