C1QL4 - complement C1q like 4 Gene

Homo sapiens

Also known as CTRP11; C1QTNF11

Gene ID: 338761 | Gene type: protein coding

About C1QL4

Cytogenetic location: 12q13.12 Genomic coordinates (GRCh38): 12:49,332,409-49,337,188 (from NCBI)

This gene has 1 transcript (splice variant), 261 orthologues and 23 paralogues. Low expression observed in reference dataset.

Summary

Predicted to enable identical protein binding activity. Predicted to act upstream of or within negative regulation of ERK1 and ERK2 cascade; negative regulation of fat cell differentiation; and negative regulation of fibroblast proliferation. Predicted to be located in extracellular space. Predicted to be part of collagen trimer. [provided by Alliance of Genome Resources, Apr 2022]

C1QL4 Products(1)

mRNA	Protein	Name
NM_001008223.2	NP_001008224.1	complement C1q-like protein 4 precursor

C1QL4 Protein Structure

C1q

0
100
200
238 a.a.

Protein Preferred Names

Protein Names

complement C1q-like protein 4

C1q and tumor necrosis factor-related protein 11

Related Diseases

Diseases

Alias

Myositis Fibrosa

Interstitial Myositis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01725	C1QL4 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	C1QL4	VGNC	VGNC:38581
Mus musculus	C1QL4	MGD	MGI:3579909
Rattus norvegicus	C1QL4	RGD	RGD:1565968
Bos taurus	C1QL4	VGNC	VGNC:106661
Macaca mulatta	C1QL4	VGNC	VGNC:70450

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