KRT8 - keratin 8 Gene

Also Known as K8; KO; CK8; CK-8; CYK8; K2C8; CARD2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 3856

About KRT8

Cytogenetic location: 12q13.13 Genomic coordinates (GRCh38): 12:52,897,191-52,949,860 (from NCBI)

This gene has 18 transcripts (splice variants), 116 orthologues, 68 paralogues and is associated with 1 phenotype. Biased expression in colon (RPKM 581.2), small intestine (RPKM 486.1) and 13 other tissues.

Summary

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

KRT8 Products (3)

mRNA Protein Name
NM_001256282.2 NP_001243211.1 keratin, type II cytoskeletal 8 isoform 1
NM_001256293.2 NP_001243222.1 keratin, type II cytoskeletal 8 isoform 2
NM_002273.4 NP_002264.1 keratin, type II cytoskeletal 8 isoform 2

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10852826 GOA
enables scaffold protein binding IPI
IPI: Inferred from physical interaction
10852826 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
15846844 GOA
located in intermediate filament IDA
IDA: Inferred from direct assay
10852826 GOA
located in keratin filament IPI
IPI: Inferred from physical interaction
10852826 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

KRT8 Protein Structure

Filament

Filament: Intermediate filament protein (90 - 401)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 483 a.a.
Protein Preferred Names Protein Names

keratin, type II cytoskeletal 8

  • cytokeratin-8

KRT8 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
KRT8 P05787 KRT13 Homo sapiens A1A4E9
Y2H Prey Pooling
25416956
Intra
KRT8 P05787 KRT13 Homo sapiens A1A4E9
Validated Y2H
25416956
Intra
KRT8 P05787 KRT40 Homo sapiens Q6A162
Y2H Prey Pooling
25416956
Intra
KRT8 P05787 KRT40 Homo sapiens Q6A162
Y2H Prey Pooling
32296183
Intra
KRT8 P05787 KRT40 Homo sapiens Q6A162
Validated Y2H
25416956
Intra
KRT8 P05787 KRT40 Homo sapiens Q6A162
Validated Y2H
32296183
Intra
KRT8 P05787 KRT40 Homo sapiens Q6A162
Y2H Array
32296183
Intra
KRT8 P05787 KRT34 Homo sapiens O76011
Y2H Array
32296183
Intra
KRT8 P05787 KRT34 Homo sapiens O76011
Y2H Prey Pooling
32296183
Intra
KRT8 P05787 KRT38 Homo sapiens O76015
Y2H Array
32296183
Intra
KRT8 P05787 KRT38 Homo sapiens O76015
Y2H Array
31515488
Intra
KRT8 P05787 KRT38 Homo sapiens O76015
Y2H Prey Pooling
32296183
Intra
KRT8 P05787 KRT33B Homo sapiens Q14525
Y2H Prey Pooling
32296183
Intra
KRT8 P05787 KRT33B Homo sapiens Q14525
Validated Y2H
32296183
Intra
KRT8 P05787 KRT33B Homo sapiens Q14525
Y2H Array
32296183
Intra
KRT8 P05787 KRT35 Homo sapiens Q92764
Validated Y2H
32296183
Intra
KRT8 P05787 KRT35 Homo sapiens Q92764
Y2H Array
32296183
Intra
KRT8 P05787 KRT35 Homo sapiens Q92764
Y2H Prey Pooling
32296183
Intra
KRT8 P05787 NEK6 Homo sapiens Q9HC98-4
Validated Y2H
32296183
Intra
KRT8 P05787 CEP57 Homo sapiens Q86XR8-3
Y2H Array
32296183
Intra
KRT8 P05787 CEP57 Homo sapiens Q86XR8-3
Y2H Prey Pooling
32296183
Intra
KRT8 P05787 CEP57 Homo sapiens Q86XR8-3
Validated Y2H
32296183
Intra
KRT8 P05787 KRT36 Homo sapiens O76013-2
Y2H Array
32296183
Intra
KRT8 P05787 KRT36 Homo sapiens O76013-2
Y2H Prey Pooling
32296183
Intra
KRT8 P05787 KRT25 Homo sapiens Q7Z3Z0
Y2H Prey Pooling
32296183
Intra
KRT8 P05787 KRT25 Homo sapiens Q7Z3Z0
Validated Y2H
32296183
Intra
KRT8 P05787 KRT25 Homo sapiens Q7Z3Z0
Y2H Array
32296183
Intra
KRT8 P05787 KRT28 Homo sapiens Q7Z3Y7
Y2H Prey Pooling
32296183
Intra
KRT8 P05787 KRT28 Homo sapiens Q7Z3Y7
Validated Y2H
32296183
Intra
KRT8 P05787 KRT28 Homo sapiens Q7Z3Y7
Y2H Array
32296183
Intra
KRT8 P05787 KRT24 Homo sapiens Q2M2I5
Y2H Prey Pooling
32296183
Intra
KRT8 P05787 KRT24 Homo sapiens Q2M2I5
Validated Y2H
32296183
Intra
KRT8 P05787 KRT24 Homo sapiens Q2M2I5
Y2H Array
32296183
Intra
KRT8 P05787 KRT18 Homo sapiens P05783
Cosedimentation
10954706
Intra
KRT8 P05787 KRT18 Homo sapiens P05783
Cosedimentation
11684708
Intra
KRT8 P05787 KRT18 Homo sapiens P05783
Y2H Array
32296183
Intra
KRT8 P05787 KRT18 Homo sapiens P05783
Y2H
10954706
Intra
KRT8 P05787 KRT18 Homo sapiens P05783
Y2H Prey Pooling
32296183
Intra
KRT8 P05787 KRT18 Homo sapiens P05783
Y2H
21988832
Intra
KRT8 P05787 KRT18 Homo sapiens P05783
Crosslink
30021884
Intra
KRT8 P05787 KRT27 Homo sapiens Q7Z3Y8
Y2H Array
32296183
Intra
KRT8 P05787 KRT27 Homo sapiens Q7Z3Y8
Y2H Prey Pooling
32296183
Intra
KRT8 P05787 KRT27 Homo sapiens Q7Z3Y8
Validated Y2H
32296183
Intra
KRT8 P05787 CFTR Homo sapiens P13569
SPR
22038833
Intra
KRT8 P05787 CFTR Homo sapiens P13569
Confocal
22038833
Intra
KRT8 P05787 CFTR Homo sapiens P13569
PLA
22038833
Intra
KRT8 P05787 VIM Homo sapiens P08670
Anti Bait CoIP
15846844
Intra
KRT8 P05787 VIM Homo sapiens P08670
Crosslink
30021884
Intra
KRT8 P05787 KRT16 Homo sapiens P08779
Validated Y2H
32296183
Intra
KRT8 P05787 KRT16 Homo sapiens P08779
Y2H Array
32296183
Intra
KRT8 P05787 KRT16 Homo sapiens P08779
Y2H Prey Pooling
32296183
Intra
KRT8 P05787 GRB2 Homo sapiens P62993
Y2H Pooling
20936779
Intra
KRT8 P05787 KRT15 Homo sapiens P19012
Validated Y2H
32296183
Intra
KRT8 P05787 KRT15 Homo sapiens P19012
Y2H Array
32296183
Intra
KRT8 P05787 KRT15 Homo sapiens P19012
Validated Y2H
25416956
Intra
KRT8 P05787 KRT15 Homo sapiens P19012
Y2H Prey Pooling
32296183
Intra
KRT8 P05787 KRT19 Homo sapiens P08727
Y2H Prey Pooling
32296183
Intra
KRT8 P05787 KRT19 Homo sapiens P08727
Validated Y2H
32296183
Intra
KRT8 P05787 KRT19 Homo sapiens P08727
Y2H Array
32296183
Intra
KRT8 P05787 IKBKG Homo sapiens Q9Y6K9
Anti Tag CoIP
21988832
Intra
KRT8 P05787 PKP1 Homo sapiens Q13835-2
Far-WB
10852826
Intra
KRT8 P05787 KRT31 Homo sapiens Q15323
Validated Y2H
32296183
Intra
KRT8 P05787 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Intra
KRT8 P05787 KRT31 Homo sapiens Q15323
Y2H Array
25416956
Intra
KRT8 P05787 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Cross
KRT8 P05787 tax Human T-cell leukemia virus 1 P14079
Y2H Array
22458338
Cross
KRT8 P05787 tax Human T-cell leukemia virus 1 P14079
MAPPIT
22458338
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant KRT8 Proteins

Cat. No. Product Name Accession Purity
HY-P72052 KRT8 Protein, Human (sf9, His-Myc) P05787-1 (M1-K483) ≥ 90%, as determined by reducing SDS-PAGE.

KRT8 Antibodies

Cat. No. Product Name Application Reactivity
HY-P82890 Phospho-Cytokeratin 8 (Ser23) Antibody (YA2635) WB, IHC-F, IHC-P, ICC/IF, IP Human
HY-P82890A Phospho-Cytokeratin 8 (Ser23) Antibody (YA2635)(PBS only) WB, IHC-F, IHC-P, ICC/IF, IP Human
HY-P83260 Cytokeratin 8 Antibody (YA3005) WB, IHC-P, ICC/IF, IP, FC Human, Mouse
HY-P83965 Cytokeratin 8 Antibody (YA3662) WB, IHC-P, ICC/IF, ELISA Human
HY-P83965A Cytokeratin 8 Antibody (YA3662)(PBS only) WB, IHC-P, ICC/IF, ELISA Human
HY-P85904 Cytokeratin 8/18 Antibody (YA5596) IHC-P, WB, ICC/IF, ELISA Human, Mouse, Rat
HY-P86058 Cytokeratin 8/18 Antibody (YA5750) IHC-P, ELISA Human, Mouse, Rat
HY-P86504 Cytokeratin 8 Antibody (YA6196) WB, IHC-P, ICC/IF, IP, FC, IF-Tissue Human, Mouse, Rat
HY-P89399M Cytokeratin 8 Antibody (AF488) (YA6196) ICC/IF, FC, IF-Tissue Human

Related Diseases

Diseases Alias
Cryptogenic Cirrhosis

  • Cirrhosis, Cryptogenic

  • Cirrhosis, Cryptogenic, Susceptibility To
Hidrocystoma

  • Apocrine Cystadenoma

  • Eccrine Hidrocystoma

  • Eccrine Cystadenoma

  • Eccrine Hidrocystoma Of Skin

  • Apocrine Adenoma
Epithelioid Sarcoma

  • Epithelioid Cell Sarcoma

  • Sarcoma Epithelioid

  • Sarcoma, Epithelioid
Papilloma

  • Papillomatosis
Craniopharyngioma

  • Neoplasm Of Rathke'S Pouch

  • Adamantinomatous Tumor

  • Craniopharyngeal Duct Tumor

  • Dysodontogenic Epithelial Tumor

  • Rathke'S Pouch Tumor
Ameloblastoma

  • Adenoameloblastoma
Liver Disease

  • Liver Failure

  • Liver Diseases

  • Abnormality Of The Liver

  • Liver Dysfunction

  • Disorder Of Liver

  • Hepatic Disorder

  • Hepatic Disease

  • Disease Of Bilirubin Metabolism

  • Disorder Of Bilirubin Metabolism

  • Liver Decompensation

  • Liver Function Failure

  • Hepatic Failure Nos

  • Liver Failure Nos

  • End Stage Liver Disease

  • Decompensated Liver Failure

  • Decompensation Of Liver Function

  • Hepatic Decompensation

  • Hepatic Insufficiency

  • Liver Cell Necrosis With Hepatic Failure

  • Liver Insufficiency

  • Decompensated Liver Disease

  • End Stage Liver Failure

  • Liver Necrosis With Hepatic Failure
Idiopathic Corneal Edema
Breast Ductal Carcinoma

  • Ductal Breast Carcinoma

  • Duct Carcinoma

  • Carcinoma, Ductal

  • Mammary Ductal Carcinoma

  • Ductal Carcinoma
Breast Fibroadenoma

  • Fibroadenoma

  • Fibroadenoma Of Breast

  • Juvenile Fibroadenoma Of Breast

  • Cellular Fibroadenoma

  • Complex Fibroadenoma Of Breast

  • Juvenile Fibroadenoma

  • Fibroadenoma Nos

  • Fibroadenoma Unspecified Site
Brooke-Spiegler Syndrome

  • Cyld Cutaneous Syndrome

  • Spiegler-Brooke Syndrome

  • Familial Cylindromatosis

  • BRSS

  • Bss

  • Sbs

  • Multiple Familial Trichoepithelioma

  • Ancell-Spiegler Cylindromas

  • Familial Multiple Trichoepithelioma

  • Trichoepithelioma

  • Fc

  • Mft

  • Multiple Familial Trichoepitheliomas

  • Ccs

  • Turban Tumor Syndrome

  • Schilbach-Rott Syndrome

  • Eccrine Dermal Cylindroma

  • Familial Multiple Trichoepitheliomata
Hemangioblastoma

  • Capillary Hemangioblastoma
Angiosarcoma

  • Hemangiosarcoma
Leukoplakia

  • Leukoplakia Of Gingiva

  • Leukoplakia Of Oral Epithelium

  • Leucoplakia Of Oral Mucosa

  • Leukokeratosis Of Oral Mucosa
Cervical Squamous Cell Carcinoma

  • Squamous Cell Carcinoma Of The Cervix Uteri

  • Squamous Cell Carcinoma Of Cervix
Autoimmune Hepatitis

  • Aih

  • Hepatitis, Autoimmune

  • Autoimmune Chronic Active Hepatitis

  • Autoimmune Hepatitis With Centrilobular Necrosis

  • Autoimmune Chronic Hepatitis

  • Hepatitis Autoimmune
Oncocytoma

  • Oxyphilic Adenoma

  • Follicular Adenoma, Oxyphilic Cell

  • Adenoma, Oxyphilic

  • Hurthle Cell Tumor

  • Oncocytic Neoplasm
Adenoid Squamous Cell Carcinoma

  • Acantholytic Squamous Cell Carcinoma

  • Adenocarcinoma With Squamous Metaplasia

  • Adenoacanthoma

  • Pseudoglandular Squamous Carcinoma
Odontoma
Hepatitis

  • Chronic Hepatitis

  • Chronic Persistent Hepatitis

  • Acute Hepatitis

  • Hepatitis, Chronic

  • Acute And Subacute Liver Necrosis

  • Acute/Subac. Necrosis Of Liver

  • Animal Hepatitis

  • Hepatitis Chronic

  • Hepatitis A

  • Hepatitis, Animal

  • Hepatitis Due To Toxoplasmosis

  • Hepatitis In Toxoplasmosis

  • Toxoplasmal Hepatitis

  • Chronic Hepatitis, Unspecified

  • Chronic Active Hepatitis Nec

  • Other Specified Chronic Hepatitis

  • Chronic Persistent Hepatitis Nec

  • Chronic Lobular Hepatitis Nec
Cervical Intraepithelial Neoplasia

  • CIN
Adenosquamous Carcinoma

  • Adenosquamous Cell Carcinoma

  • Mixed Adenocarcinoma And Squamous Carcinoma

  • Carcinoma Adenosquamous

  • Carcinoma, Adenosquamous
Sertoli Cell Tumor

  • Tubular Androblastoma
Skin Carcinoma

  • Skin Cancer

  • Carcinoma Of Skin

  • Ca - Skin Cancer

  • Cancer Of Skin

  • Malignant Neoplasm Of Skin

  • Melanoma And Non-Melanoma Skin Cancer

  • Skin Cancers

  • Cancer, Skin
Vulvar Sebaceous Carcinoma
Cervical Clear Cell Adenocarcinoma

  • Clear Cell Carcinoma Of The Cervix Uteri
Sweat Gland Cancer

  • Sweat Gland Carcinoma

  • Malignant Neoplasm Of Sweat Gland

  • Malignant Tumor Of The Sweat Gland

  • Carcinoma Of The Sweat Gland

  • Primary Malignant Neoplasm Of Sweat Gland

  • Sweat Gland Neoplasms
Mucoepidermoid Carcinoma

  • Mec

  • Salivary Gland Mucoepidermoid Carcinoma

  • C3772

  • Carcinoma Mucoepidermoid

  • Carcinoma, Mucoepidermoid
Viral Hepatitis

  • Animal Viral Hepatitis

  • Hepatitis, Viral, Animal

  • Human Viral Hepatitis

  • Viral Hepatitis With Hepatic Coma
Pancreatic Ductal Carcinoma

  • Carcinoma, Pancreatic Ductal

  • Malignant Neoplasm Of Duct Of Wirsung

  • Pancreatic Duct Cancer

  • Carcinoma Pancreatic Ductal
Uterine Carcinosarcoma

  • Carcinosarcoma Of The Corpus Uteri

  • Mixed Mullerian Sarcoma Of Uterus

  • Malignant Mixed Müllerian Tumor Of The Corpus Uteri

  • Malignant Mixed Müllerian Tumor Of Corpus Uteri

  • Mixed Müllerian Cancer Of Corpus Uteri

  • Malignant Mixed Mullerian Tumor Of The Corpus Uteri

  • Mixed Mullerian Cancer Of Corpus Uteri

  • Uterine Corpus Carcinosarcoma
Liver Cirrhosis

  • Cirrhosis

  • Cirrhosis Of Liver

  • CIRRH

  • Cryptogenic Cirrhosis

  • Cirrhosis, Cryptogenic

  • Cirrhosis Nos
Apocrine Adenoma

  • Tubular Apocrine Adenoma
Parachordoma
Adamantinoma Of Long Bones

  • Long Bone Adamantinoma
Merkel Cell Carcinoma

  • Trabecular Adenocarcinoma

  • Cutaneous Neuroendocrine Carcinoma

  • Trabecular Carcinoma

  • Carcinoma, Merkel Cell

  • Merkel Cell Cancer

  • Merkle Tumors

  • Mcc

  • Carcinoma Merkel Cell
Eccrine Papillary Adenoma

  • Papillary Eccrine Adenoma

  • Eccrine Papillary Adenoma Of Skin
Apocrine Sweat Gland Neoplasm

  • Apocrine Tumor

  • Apocrine Neoplasm
Bladder Cancer

  • Urinary Bladder Cancer

  • Bladder Carcinoma

  • Urinary Bladder Carcinoma

  • Bladder Neoplasm

  • Bladder Tumor

  • Cancer, Bladder

  • Malignant Neoplasm Of Urinary Bladder

  • Carcinoma Of Bladder

  • Bladder Cancer, Somatic

  • Tumor Of The Bladder

  • Carcinoma Of Urinary Bladder

  • Bladder Carcinoma Urinary

  • Cancer Of The Urinary Bladder

  • Cancer, Urinary Bladder

  • Malignant Bladder Neoplasm

  • Malignant Bladder Tumor

  • Neoplasm Of The Bladder

  • Neoplasm Of The Urinary Bladder

  • Tumor Of The Urinary Bladder

  • Urinary Bladder Neoplasm

  • BLC

  • Urothelial Carcinoma Of The Bladder

  • Bladder Tumors

  • Urinary Bladder Neoplasms

  • Bladder Cancer Nos

  • Vesical Cancer Nos

  • Malignant Neoplasm Of Bladder, Part Unspecified

  • Malignant Tumour Of Urinary Bladder

  • Primary Malignant Neoplasm Of Bladder
Sarcoma, Synovial

  • Synovial Sarcoma

  • Synovialosarcoma

  • Synovial Cell Sarcoma

  • Sarcoma Synovial
Breast Cancer

  • Breast Carcinoma

  • Male Breast Cancer

  • Breast Cancer, Familial

  • Malignant Neoplasm Of Breast

  • Breast Cancer, Susceptibility To

  • Breast Cancer, Early-Onset

  • Malignant Tumor Of Breast

  • Carcinoma Of Male Breast

  • Breast Cancer, Invasive Ductal

  • Breast Cancer, Protection Against

  • Breast Cancer, Somatic

  • Breast Cancer, Male

  • Breast Cancer, Lobular, Somatic

  • Breast Tumor

  • Mammary Cancer

  • Mammary Tumor

  • Malignant Neoplasm Of Male Breast

  • Mammary Carcinoma

  • Male Breast Carcinoma

  • Familial Cancer Of Breast

  • Invasive Ductal Breast Carcinoma

  • Breast Cancer Susceptibility

  • Breast Cancer, Male, Susceptibility To

  • Breast Cancer, Early-Onset, Susceptibility To

  • Malignant Tumor Of The Breast

  • Mammary Neoplasm

  • Primary Breast Cancer

  • Neoplasm Of Male Breast

  • Carcinoma Of Breast

  • Breast Cancer In Men

  • Familial Breast Cancer

  • Cancer Of Breast

  • BC

  • Breast Cancer Familial

  • Breast Cancer Familial Male

  • Breast Cancer, Familial Male

  • Breast Male Carcinoma

  • Breast Neoplasms

  • Breast Neoplasms, Male

  • Mammary Tumors

  • Mammary Carcinomas

  • Cancer, Breast

  • Cancer, Breast, Susceptibility

  • Invasive Breast Ductal Carcinoma

  • Breast Neoplasm

  • Susceptibility To Breast Cancer

  • Mammary Neoplasms

  • Animal Mammary Neoplasms

  • Primary Malignant Neoplasm Of Breast

  • Infiltrating Ductal Carcinoma Of Breast

  • Infiltrating Duct Carcinoma Of Unspecified Site

  • Infiltrating Ductular Carcinoma Of Unspecified Site

  • Invasive Breast Carcinoma Of No Special Type

  • Microinvasive Carcinoma Of Breast

  • Carcinoma With Apocrine Differentiation
Colorectal Cancer

  • Colon Cancer

  • Colorectal Carcinoma

  • Colon Carcinoma

  • Colorectal Cancer, Susceptibility To

  • Carcinoma Of Colon

  • CRC

  • Colorectal Cancer With Chromosomal Instability, Somatic

  • Colon Cancer, Somatic

  • Colon Cancer, Susceptibility To

  • Colonic Neoplasms

  • Colorectal Neoplasms

  • Colorectal Cancer, Somatic

  • Colon Cancer, Advanced, Somatic

  • Colonic Carcinoma

  • Colorectal Carcinomas

  • Colon Cancers

  • Colorectal Cancers

  • Cancer, Colorectal, Somatic

  • Cancer, Colon

  • Cancer, Colorectal, Susceptibility To

  • Colorectal Neoplasm

  • Colonic Neoplasm

  • Malignant Tumor Of Colon
Pancreatic Serous Cystic Neoplasm

  • Pancreatic Serous Neoplasm
Mucinous Tubular And Spindle Renal Cell Carcinoma

  • Mucinous Tubular And Spindle Cell Renal Carcinoma
Prostate Cancer

  • Prostate Carcinoma

  • Prostate Cancer, Familial

  • Prostate Neoplasm

  • Prostate Cancer, Somatic

  • Prostate Cancer, Susceptibility To

  • Prostatic Cancer

  • Prostatic Neoplasms

  • Hereditary Prostate Cancer

  • Prostatic Neoplasm

  • Cancer Of Prostate

  • Carcinoma Of Prostate

  • Familial Prostate Cancer

  • Familial Prostate Carcinoma

  • Malignant Tumor Of Prostate

  • Malignant Neoplasm Of Prostate

  • Prostate Cancer, Familial, Susceptibility To

  • Malignant Tumor Of The Prostate

  • Ngp - New Growth Of Prostate

  • Tumor Of The Prostate

  • Prostate Cancer, Hereditary

  • Cancer Of The Prostate

  • Malignant Neoplasm Of The Prostate

  • Prostatic Carcinoma

  • PC

  • Prca

  • Cancer, Prostate

  • Malignant Prostatic Tumour

  • Malignant Tumour Of Prostate

  • Primary Prostate Cancer

  • Primary Malignant Neoplasm Of Prostate

  • Prostate Gland Cancer
Lymphoepithelioma-Like Thymic Carcinoma

  • Lymphoepithelioma-Like Carcinoma Of The Thymus

  • Thymic Lymphoepithelioma-Like Carcinoma
Tibial Adamantinoma

  • Tibial Adamantinoma Morphology
Breast Secretory Carcinoma

  • Secretory Breast Carcinoma

  • Juvenile Breast Carcinoma

  • Juvenile Carcinoma Of The Breast

  • Juvenile Secretory Carcinoma Of Breast

  • Juvenile Breast Cancer

  • Sbc

  • Secretory Carcinoma Of The Breast
Cholangiocarcinoma

  • Cholangiocarcinoma, Susceptibility To

  • Extrahepatic Cholangiocarcinoma

  • Intrahepatic Cholangiocarcinoma

  • Chlc

  • Chlc, Susceptibility To

  • Cc

  • Cholangiocarcinoma Of Biliary Tract

  • Cholangiocellular Carcinoma

  • Distal Cholangiocarcinoma

  • Perihilar Cholangiocarcinoma

  • Bile Duct Cancer

  • Cca

  • Adult Primary Cholangiocellular Carcinoma

  • Bile Duct Carcinoma
Subareolar Duct Papillomatosis

  • Adenoma Of The Nipple
Nipple Benign Neoplasm

  • Tumor Of Nipple
Small Intestine Leiomyosarcoma

  • Leiomyosarcoma Of The Small Bowel

  • Smooth Muscle Connective Tissue Tumor

  • Leiomyosarcoma Of Small Intestine
Hepatoid Adenocarcinoma
Intrahepatic Gall Duct Cancer

  • Malignant Neoplasm Of Intrahepatic Bile Ducts

  • Malignant Neoplasm Of Intrahepatic Gall Duct

  • Ca Intrahepatic Bile Ducts

  • Malignant Neoplasm Of Intrahepatic Biliary Passages

  • Intrahepatic Bile Duct Carcinoma
Keratoacanthoma

  • Ka - [Keratoacanthoma]

  • Well-Differentiated Squamous Cell Carcinoma
Sweat Gland Benign Neoplasm

  • Neoplasm Of Sweat Gland

  • Sweat Gland Tumor

  • Tumor Of The Sweat Gland

  • Sweat Gland Neoplasms

  • Sweat Gland Neoplasm
Epidermolysis Bullosa Simplex Localized Type

  • Epidermolysis Bullosa Simplex, Weber-Cockayne Type

  • Weber-Cockayne Syndrome

  • Ebs-Loc

  • Epidermolysis Bullosa Simplex Of Palms And Soles

  • Epidermolysis Bullosa Simplex Weber-Cockayne Type

  • Epidermolysis Bullosa Simplex, Localized

  • Epidermolysis Bullosa Of Hands And Feet

  • Weber-Cockayne Type Epidermolysis Bullosa Simplex

  • Localized Epidermolysis Bullosa Simplex

  • Localized Ebs
Squamous Cell Bile Duct Carcinoma

  • Bile Duct Squamous Cell Carcinoma
Cervical Adenocarcinoma

  • Adenocarcinoma Cervix Uteri

  • Adenocarcinoma Of Cervix

  • Adenocarcinoma Of The Uterine Cervix

  • Adenocarcinoma Of The Cervix Uteri
Endometrium Carcinoma In Situ

  • Carcinoma In Situ Of Endometrium

  • Endometrial Carcinoma In Situ
Cribriform Carcinoma

  • Ductal Carcinoma, Cribriform Type

  • Carcinoma Cribriform

  • Carcinoma, Cribriform
Gallbladder Cancer

  • Gallbladder Carcinoma

  • Gallbladder Neoplasm

  • Malignant Neoplasm Of Gallbladder

  • Malignant Tumour Of Gallbladder

  • Gallbladder Ca

  • Localized Malignant Gallbladder Neoplasm

  • Malignant Tumor Of The Gallbladder

  • Tumor Of The Gallbladder

  • Cancer Of The Gallbladder

  • Carcinoma Gallbladder

  • Carcinoma Of Gallbladder

  • Gallbladder Neoplasms

  • Malignant Neoplasm Of Gallbladder Localized

  • Cancer Of Gallbladder

  • Primary Malignant Neoplasm Of Gallbladder
Ectopic Thymus
Pancreatic Cancer

  • Pancreatic Carcinoma

  • Carcinoma Of Pancreas

  • Familial Pancreatic Carcinoma

  • Pancreatic Neoplasm

  • Pancreatic Carcinoma, Familial

  • Malignant Neoplasm Of Pancreas

  • Pancreatic Acinar Carcinoma

  • Pancreatic Tumor

  • Familial Pancreatic Cancer

  • Neoplasm Of The Pancreas

  • Cancer Of The Pancreas

  • Pancreatic Carcinoma, Somatic

  • Pancreatic Cancer, Somatic

  • Ca Body Of Pancreas

  • Ca Head Of Pancreas

  • Ca Tail Of Pancreas

  • Malignant Neoplasm Of Body Of Pancreas

  • Malignant Neoplasm Of Head Of Pancreas

  • Malignant Neoplasm Of Tail Of Pancreas

  • Pancreas Neoplasm

  • Exocrine Cancer

  • Exocrine Pancreas Carcinoma

  • Hereditary Pancreatic Cancer

  • Hereditary Pancreatic Carcinoma

  • PNCA

  • Pancreatic Cancer, Susceptibility To

  • Carcinoma Of Head Of Pancreas

  • Pancreatic Neoplasms

  • Pancreatic Tumors

  • Cancer, Pancreatic

  • Cancer Of Pancreas

  • Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Vulvar Leiomyosarcoma
Benign Breast Adenomyoepithelioma

  • Benign Adenomyoepithelioma Of The Breast
Joubert Syndrome 8

  • JBTS8

  • Joubert Syndrome, Type 8
Breast Carcinoma In Situ

  • Carcinoma In Situ Of Breast

  • Non-Infiltrating Carcinoma Of Breast

  • Breast Cancer In Situ
Intraductal Breast Benign Neoplasm
Basaloid Squamous Cell Carcinoma

  • Basaloid Carcinoma
Lung Cancer

  • Lung Carcinoma

  • Non-Small Cell Lung Carcinoma

  • Lung Cancer, Susceptibility To

  • Lung Cancer, Protection Against

  • Adenocarcinoma Of Lung, Somatic

  • Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer

  • Lung Neoplasm

  • Carcinoma Of Lung

  • Lung Non-Small Cell Carcinoma

  • Non-Small Cell Lung Cancer

  • Nsclc

  • Lung Neoplasms

  • Malignant Neoplasm Of Lung

  • Alveolar Cell Carcinoma

  • Nonsmall Cell Lung Cancer, Somatic

  • Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer, Susceptibility To

  • Lung Cancer, Somatic

  • Lung Cancer, Resistance To

  • Cancer Of Lung

  • Cancer Of Bronchus

  • Cancer Of The Lung

  • Lung Malignancies

  • Lung Malignant Tumors

  • Malignant Lung Tumor

  • Malignant Tumor Of Lung

  • Pulmonary Cancer

  • Pulmonary Carcinoma

  • Pulmonary Neoplasms

  • Respiratory Carcinoma

  • LNCR

  • Adenocarcinoma Of Lung

  • Neoplasm Of Lung

  • Cancer Lung

  • Carcinoma Non-Small Cell Lung

  • Carcinoma, Non-Small-Cell Lung

  • Lung Cancers

  • Lung Carcinomas

  • Cancer, Lung

  • Cancer, Lung, Non-Small Cell

  • Primary Malignant Neoplasm Of Lung

  • Bronchioloalveolar Adenocarcinoma
Rete Ovarii Benign Neoplasm
Rete Ovarii Adenoma

  • Adenoma Of Rete Ovarii
Chondroid Chordoma
Polyp Of Corpus Uteri

  • Endometrial/Uterine Polyp

  • Polyp Of Endometrium

  • Polyp Of The Uterus

  • Polyp, Uterus
Wrinkly Skin Syndrome

  • WSS

  • Wrinkled Skin Syndrome
Synovium Neoplasm

  • Synovial Neoplasm

  • Tumor Of Synovium
Ductal Carcinoma In Situ

  • Noninfiltrating Intraductal Carcinoma
Melanoma, Uveal

  • Uveal Melanoma

  • Choroidal Melanoma

  • Melanoma Of Uvea

  • Iris Melanoma

  • Malignant Melanoma Of Choroid

  • Malignant Melanoma Of Iris
Focal Segmental Glomerulosclerosis

  • Familial Idiopathic Steroid-Resistant Nephrotic Syndrome

  • Focal Glomerulosclerosis

  • Fsgs

  • Segmental Glomerulosclerosis

  • Glomerulosclerosis, Focal Segmental

  • Fgs

  • Focal Glomerular Sclerosis

  • Familial Idiopathic Nephrotic Syndrome

  • Focal Sclerosis With Hyalinosis

  • Glomerulosclerosis, Focal

  • Glomerulosclerosis Focal

  • Glomerulosclerosis, Segmental, Focal

  • Focal Segmental Glomerulosclerosis, Not Otherwise Specified
Sweat Gland Disease

  • Sweat Gland Diseases
In Situ Carcinoma

  • Carcinoma In Situ
Hepatocellular Carcinoma

  • Liver Cancer

  • Primary Liver Cancer

  • HCC

  • Hepatoma

  • Malignant Neoplasm Of Liver

  • Liver Neoplasms

  • Cancer, Hepatocellular

  • Liver Cell Carcinoma

  • Lcc

  • Hepatoblastoma, Somatic

  • Hepatic Cancer

  • Primary Malignant Neoplasm Of Liver

  • Rare Tumor Of Liver And Intrahepatic Biliary Tract

  • Hepatocellular Carcinoma, Somatic

  • Hepatocellular Carcinoma, Childhood Type, Somatic

  • Hepatocellular Cancer, Somatic

  • Ca Liver - Primary

  • Hepatic Neoplasm

  • Malignant Hepato-Biliary Neoplasm

  • Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

  • Malignant Neoplasm Of Liver, Primary

  • Malignant Tumor Of Liver

  • Neoplasm Of Liver

  • Non-Resectable Primary Hepatic Malignant Neoplasm

  • Resectable Malignant Neoplasm Of Liver

  • Resectable Malignant Neoplasm Of The Liver

  • Primary Liver Carcinoma

  • Primary Malignant Liver Neoplasm

  • Primary Cancer Of Liver

  • Primary Tumor Of The Liver

  • Rare Tumor Of Liver And Ibt

  • Hepatocellular Cancer

  • Neoplasm Of The Liver

  • Carcinoma, Hepatocellular

  • Hepatomas

  • Liver Neoplasm

  • Liver Carcinoma

  • Liver And Intrahepatic Biliary Tract Carcinoma

  • Malignant Hepatobiliary Neoplasm

  • Adult Primary Hepatocellular Carcinoma

  • Hepatoblastoma

  • Carcinoma Of Liver

  • Malignant Liver Tumour

  • Malignant Hepatic Tumour
Breast Benign Neoplasm

  • Benign Tumour Of Breast

  • Benign Neoplasm Of Female Breast
Thoracic Benign Neoplasm

  • Benign Neoplasm Of Thorax
Basal Cell Carcinoma

  • Basal Cell Cancer

  • Basal Cell Neoplasm

  • Basal Cell Carcinoma Of Skin

  • Malignant Basal Cell Tumor

  • Basal Cell Tumor

  • Epithelioma Basal Cell

  • Malignant Basal Cell Neoplasm

  • Rodent Ulcer

  • Carcinoma Basal Cell

  • Neoplasms, Basal Cell

  • Basal Cell Carcinomas

  • Experimental Organism Basal Cell Carcinoma

  • Nodulo-Ulcerative Basal Cell Carcinoma

  • Basalioma

  • Basal Cell Epithelioma Of Skin

  • Bcc - [Basal Cell Carcinoma] Of Skin

  • Rodent Ulcer Of Skin

  • Rodent Ulcer Of Unspecified Site

  • Basal Cell Epithelioma Of Unspecified Site
Breast Lobular Carcinoma

  • Cancer, Breast, Lobular

  • Lobular Breast Carcinoma
Pre-Malignant Neoplasm
Prostate Signet Ring Cell Adenocarcinoma

  • Prostate Signet Ring Cell Carcinoma

  • Signet Ring Cell Carcinoma Of Prostate

  • Acinar Prostate Adenocarcinoma, Signet Ring Variant
Ovarian Cancer

  • Ovarian Carcinoma

  • Ovarian Neoplasm

  • Malignant Tumour Of Ovary

  • Cancer Of The Ovary

  • Epithelial Ovarian Cancer

  • Neoplasm Of Ovary

  • Ovarian Neoplasms

  • Ovarian Cancers

  • Malignant Neoplasm Of Ovary

  • Primary Malignant Neoplasm Of Ovary

  • Ovarian Cancer, Somatic

  • Malignant Ovarian Tumor

  • Ovary Neoplasm

  • Primary Ovarian Cancer

  • Tumor Of The Ovary

  • Malignant Neoplasm Of The Ovary

  • Malignant Tumor Of The Ovary

  • Ovarian Malignant Tumor

  • OC

  • Ovarian Carcinomas

  • Cancer, Ovarian

  • Cancer Of Ovary

  • Ovary Cancer

  • Ca Ovary
Renal Cell Carcinoma, Nonpapillary

  • Renal Cell Carcinoma

  • RCC

  • Nonpapillary Renal Cell Carcinoma

  • Clear Cell Renal Cell Carcinoma

  • Hypernephroma

  • Adenocarcinoma Of Kidney

  • Renal Carcinoma, Chromophobe, Somatic

  • Clear Cell Carcinoma Of Kidney

  • Clear-Cell Metastatic Renal Cell Carcinoma

  • Clear Cell Renal Carcinoma

  • Renal Cell Carcinoma, Somatic

  • Conventional Renal Cell Carcinoma

  • Conventional Renal Cell Carcinoma

  • Renal Clear Cell Carcinoma

  • Ccrcc

  • Hereditary Clear Cell Renal Cell Carcinoma

  • Carcinoma, Renal Cell

  • Renal Cell Carcinoma, Clear Cell, Somatic

  • Renal Cell Carcinoma, Clear Cell

  • Clear Cell Kidney Carcinoma

  • Clear Cell Rcc

  • Cystic-Multilocular Variant

  • Clear Cell Renal Cell Adenocarcinoma

  • Hereditary Clear Cell Renal Cell Adenocarcinoma

  • Common Renal Cell Carcinoma

  • Crcc

  • Renal Cell Carcinoma Non-Papillary

  • Carcinoma Renal Cell

  • Renal Cell Cancer

  • Carcinoma, Renal Cell, Nonpapillary
Male Urethral Cancer

  • Male Urethral Malignant Neoplasm
Childhood Angiosarcoma

  • Paediatric Angiosarcoma

  • Paediatric Hemangiosarcoma

  • Pediatric Angiosarcoma

  • Pediatric Hemangiosarcoma
Suppression Of Tumorigenicity 12

  • Prostate Adenocarcinoma

  • Adenocarcinoma Of Prostate

  • ST12

  • Prostate Adenocarcinoma 1

  • Pac1
Prostate Stromal Sarcoma

  • Stromal Sarcoma Of The Prostate
Breast Rhabdomyosarcoma

  • Rhabdomyosarcoma Of The Breast
Salpingitis Isthmica Nodosa
Partial Third-Nerve Palsy

  • Partial Third Nerve Palsy

  • Third Nerve Palsy With Pupil Sparing

  • Third Or Oculomotor Nerve Palsy, Partial

  • Oculomotor Nerve Diseases

  • Oculomotor Nerve Paralysis
Cystic Fibrosis

  • Mucoviscidosis

  • CF

  • Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis

  • Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis

  • Cystic Fibrosis Lung Disease, Modifier Of

  • Cystic Fibrosis Of Pancreas

  • Fibrocystic Disease Of Pancreas

  • Cf - [Cystic Fibrosis]

  • Cystic Fibrosis Nos

  • Fibrocystic Disease

  • Fibrocystic Disease Of The Pancreas

  • Mucoviscidosis Of Pancreas

  • Nonproliferative Fibrocystic Disease

  • Pancreatic Cystic Fibrosis
Lung Cancer Susceptibility 3

  • Lung Adenocarcinoma

  • Adenocarcinoma Of Lung

  • LNCR3

  • Adenocarcinoma Of Lung, Susceptibility To

  • Bronchogenic Lung Adenocarcinoma

  • Nonsmall Cell Adenocarcinoma

  • Adenocarcinoma Lung

  • Lung Adenocarcinomas

  • Non-Small Cell Adenocarcinoma
Breast Adenocarcinoma

  • Mammary Adenocarcinoma

  • Adenocarcinoma Of Breast
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07467 KRT8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18137 Krt8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24612 Krt8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus KRT8 RGD RGD:2984
Mus musculus KRT8 MGD MGI:96705
Felis catus KRT8 VGNC VGNC:108196
Others KRT8 NCBI