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55827

" within the MedChemExpress (MCE) catalog. Here are the results you might be looking for.

By Targets:	Apoptosis (2) Aurora Kinase (1) IAP (2) MicroRNA (16) Phosphodiesterase (PDE) (1) PROTACs (1)
By Research Areas:	Cancer (19) Inflammation/Immunology (1)
Oligonucleotides:	miRNA mimics (4) miRNA agomirs (4) miRNA antagomirs (4) MicroRNAs (16) miRNA inhibitors (4)

Inhibitors & Agonists

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-12600

AZD5582 15+ Cited Publications	IAP Apoptosis	Cancer
AZD5582 is an antagonist of the inhibitor of apoptosis proteins (IAPs), which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC₅₀s of 15, 21, and 15 nM, respectively. AZD5582 induces apoptosis .

HY-110346

AZD5582 dihydrochloride 15+ Cited Publications	IAP Apoptosis	Cancer
AZD5582 dihydrochloride is an antagonist of the inhibitor of apoptosis proteins (IAPs), which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC₅₀s of 15, 21, and 15 nM, respectively. AZD5582 induces apoptosis .

HY-RI01731

*hsa-miR-5582-5p inhibitor*	MicroRNA	Cancer
hsa-miR-5582-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-5582-5p inhibitor hsa-miR-5582-5p inhibitor

HY-100142

Clozic ICI 55897; Clobuzarit	Phosphodiesterase (PDE)	Inflammation/Immunology
Clozic is a potential anti-arthritic agent.

HY-R01730

*hsa-miR-5582-3p mimic*	MicroRNA	Cancer
hsa-miR-5582-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-5582-3p mimic hsa-miR-5582-3p mimic

HY-R01741

*hsa-miR-5587-5p mimic*	MicroRNA	Cancer
hsa-miR-5587-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-5587-5p mimic hsa-miR-5587-5p mimic

HY-R01731

*hsa-miR-5582-5p mimic*	MicroRNA	Cancer
hsa-miR-5582-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-5582-5p mimic hsa-miR-5582-5p mimic

HY-179641

SK5527	PROTACs Aurora Kinase	Cancer
SK5527 is a selective AURKA PROTAC degrader degrading AURKA with DC₅₀ = 2 nM. SK5527 bind to NanoLuc-AURKA with an IC₅₀ of 20 nM. SK5527 effectively reduces MYCN levels in MYCN-amplified neuroblastoma cells and limited by MDR1-mediated efflux. SK5527 efficiently reduced AURKA levels in vivo. SK5527 can be used for neuroblasto2ma research .

HY-RI01741A

*hsa-miR-5587-5p antagomir*	MicroRNA	Cancer
hsa-miR-5587-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5587-5p antagomir hsa-miR-5587-5p antagomir

HY-RI01740

*hsa-miR-5587-3p inhibitor*	MicroRNA	Cancer
hsa-miR-5587-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-5587-3p inhibitor hsa-miR-5587-3p inhibitor

HY-RI01730

*hsa-miR-5582-3p inhibitor*	MicroRNA	Cancer
hsa-miR-5582-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-5582-3p inhibitor hsa-miR-5582-3p inhibitor

HY-R01731A

*hsa-miR-5582-5p agomir*	MicroRNA	Cancer
hsa-miR-5582-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5582-5p agomir hsa-miR-5582-5p agomir

HY-R01730A

*hsa-miR-5582-3p agomir*	MicroRNA	Cancer
hsa-miR-5582-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5582-3p agomir hsa-miR-5582-3p agomir

HY-RI01740A

*hsa-miR-5587-3p antagomir*	MicroRNA	Cancer
hsa-miR-5587-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5587-3p antagomir hsa-miR-5587-3p antagomir

HY-R01740

*hsa-miR-5587-3p mimic*	MicroRNA	Cancer
hsa-miR-5587-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-5587-3p mimic hsa-miR-5587-3p mimic

HY-R01740A

*hsa-miR-5587-3p agomir*	MicroRNA	Cancer
hsa-miR-5587-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5587-3p agomir hsa-miR-5587-3p agomir

HY-RI01730A

*hsa-miR-5582-3p antagomir*	MicroRNA	Cancer
hsa-miR-5582-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5582-3p antagomir hsa-miR-5582-3p antagomir

HY-RI01741

*hsa-miR-5587-5p inhibitor*	MicroRNA	Cancer
hsa-miR-5587-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-5587-5p inhibitor hsa-miR-5587-5p inhibitor

HY-RI01731A

*hsa-miR-5582-5p antagomir*	MicroRNA	Cancer
hsa-miR-5582-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5582-5p antagomir hsa-miR-5582-5p antagomir

HY-R01741A

*hsa-miR-5587-5p agomir*	MicroRNA	Cancer
hsa-miR-5587-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5587-5p agomir hsa-miR-5587-5p agomir

Tag:	His (4) Strep (1) Tag Free (1)
Source:	E. coli (5)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P703447

	BT_4683 Protein, Bacteroides thetaiotaomicron (His) Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50); Hydrolase	Others	E. coli
	BT_4683 Protein, Bacteroides thetaiotaomicron (His) is the recombinant BT_4683 protein, expressed by E. coli, with His tag.

HY-P703448

	BT_1622 Protein, Bacteroides thetaiotaomicron (His) Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50); Hydrolase	Others	E. coli
	BT_1622 Protein, Bacteroides thetaiotaomicron (His) is the recombinant BT_1622 protein, expressed by E. coli, with His tag.

HY-P703449

	BT_1636 Protein, Bacteroides thetaiotaomicron (His) Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50); Hydrolase	Others	E. coli
	BT_1636 Protein, Bacteroides thetaiotaomicron (His) is the recombinant BT_1636 protein, expressed by E. coli, with His tag.

HY-P703445

	susB Protein, Bacteroides thetaiotaomicron Glucan 1,4-alpha-glucosidase SusB; Alpha-glucosidase SusB; Glucoamylase SusB; Starch-utilization system protein B; susB; Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50); Glycosidase; Hydrolase; 3.2.1.3	Others	E. coli
	susB Protein, Bacteroides thetaiotaomicron is the recombinant susB, expressed by E. coli , with tag Free labeled tag. ,

HY-P703446

	susB Protein, Bacteroides thetaiotaomicron (His, Strep) Glucan 1,4-alpha-glucosidase SusB; Alpha-glucosidase SusB; Glucoamylase SusB; Starch-utilization system protein B; susB; Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50); Glycosidase; Hydrolase; 3.2.1.3	Others	E. coli
	susB Protein, Bacteroides thetaiotaomicron (His, Strep) is the recombinant susB, expressed by E. coli , with Strep, His labeled tag. ,

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Species
Source
Tag
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Gene ID
Molecular Weight
Purity
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Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Host:	Mouse (7) Rabbit (1)
Reactivity:	Human (8) Rat (5) Mouse (5)
Application:	IHC-P (3) ICC/IF (8) IP (1) WB (6) FC (4) ELISA (4)
Isotype:	IgG (2) IgG1 (3) IgG2a (2) IgG2b (1)
Conjugation:	Non-conjugated (8)
Clonality:	Monoclonal (6)
Modification:	Unmodified (6)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P88808

	TMEM80 Antibody (YA8492) FLJ38216; FLJ55823	ICC/IF, FC	Human
	TMEM80 Antibody (YA8492) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to TMEM80.

HY-P88808A

	TMEM80 Antibody (YA8492)(PBS only) FLJ38216; FLJ55823	ICC/IF, FC	Human
	TMEM80 Antibody (YA8492) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to TMEM80.

HY-P88066

	NUMB Antibody (YA7750) C14orf41; c14_5527; S171	WB, ICC/IF, FC	Human, Mouse, Rat
	NUMB Antibody (YA7750) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NUMB.

HY-P88066A

	NUMB Antibody (YA7750)(PBS only) C14orf41; c14_5527; S171	WB, ICC/IF, FC	Human, Mouse, Rat
	NUMB Antibody (YA7750) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NUMB.

HY-P86135

	Caspase-6 Antibody (YA5827) CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Caspase-6 Antibody (YA5827) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Caspase-6.

HY-P85835

	ERK2 Antibody (YA5527) MAPK1; ERK2; PRKM1; PRKM2; Mitogen-activated protein kinase 1; MAP kinase 1; MAPK 1; ERT1; Extracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2	WB, ICC/IF, ELISA	Human, Mouse, Rat
	ERK2 Antibody (YA5527) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to ERK2.

HY-P85895

	CD45 Antibody (YA5587) B220; CD 45; CD45; CD45 antigen; CD45R; GP180; L-CA; LCA; Leukocyte common antigen; loc; Ly-5; LY5; Ly5, homolog of; Lyt-4; OTTHUMP00000033813; OTTHUMP00000033816; OTTHUMP00000033817; OTTHUMP00000038574; Protein tyrosine phosphatase receptor type c polypeptide; Protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; Protein tyrosine phosphatase, receptor type, c polypeptide; Ptprc; PTPRC_HUMAN; Receptor-type tyrosine-protein phosphatase C; T200; T200 glycoprotein; T200 leukocyte common antigen	IHC-P, WB, ICC/IF, ELISA	Human
	CD45 Antibody (YA5587) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CD45.

HY-P85890

	Iba1 Antibody (YA5582) AIF 1; AIF-1; Aif1; AIF1 protein; AIF1_HUMAN; Allograft inflammatory factor 1; Allograft inflammatory factor 1 splice variant G; allograft inflammatory factor-1 splice variant Hara-1; balloon angioplasty responsive transcription; BART 1; G1; G1 putative splice variant of allograft inflamatory factor 1; IBA 1; IBA1; interferon gamma responsive transcript; Interferon responsive transcript 1; interferon responsive transcript factor 1; Ionized calcium binding adapter molecule 1; Ionized calcium-binding adapter molecule 1; ionized calcium-binding adapter molecule; IRT 1; IRT1; Microglia response factor; MRF1; Protein g1;	IHC-P, WB, ICC/IF, ELISA	Human, Mouse, Rat
	Iba1 Antibody (YA5582) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Iba1.

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Products	In-stock - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
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Appearance
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Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-RI01731

*hsa-miR-5582-5p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-5582-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R01730

*hsa-miR-5582-3p mimic*		MicroRNAs miRNA mimics
hsa-miR-5582-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R01741

*hsa-miR-5587-5p mimic*		MicroRNAs miRNA mimics
hsa-miR-5587-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R01731

*hsa-miR-5582-5p mimic*		MicroRNAs miRNA mimics
hsa-miR-5582-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI01741A

*hsa-miR-5587-5p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-5587-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01740

*hsa-miR-5587-3p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-5587-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI01730

*hsa-miR-5582-3p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-5582-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R01731A

*hsa-miR-5582-5p agomir*		MicroRNAs miRNA agomirs
hsa-miR-5582-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R01730A

*hsa-miR-5582-3p agomir*		MicroRNAs miRNA agomirs
hsa-miR-5582-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01740A

*hsa-miR-5587-3p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-5587-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R01740

*hsa-miR-5587-3p mimic*		MicroRNAs miRNA mimics
hsa-miR-5587-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R01740A

*hsa-miR-5587-3p agomir*		MicroRNAs miRNA agomirs
hsa-miR-5587-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01730A

*hsa-miR-5582-3p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-5582-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01741

*hsa-miR-5587-5p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-5587-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI01731A

*hsa-miR-5582-5p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-5582-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R01741A

*hsa-miR-5587-5p agomir*		MicroRNAs miRNA agomirs
hsa-miR-5587-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

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