DCAF11 ligand 2
DCAF11 ligand 2 is an E3 ligase ligand that can be used in the recruitment of DCAF11. DCAF11 ligand 2 can be connected to the BRD4 ligand (HY-78695) by a linker to synthesis of PROTAC BRD4 degrader LGF308 (HY-181756).
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- CAS No.: 24044-52-8
- Formule: C10H6N2O4S
- Masse moléculaire:250.23
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
[1]|
DCAF11 |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MCF7 | IC50 |
55.8 μM
Compound: 11a(E)
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Antiproliferative activity against human MCF7 cells after 72 hrs by SRB assay
Antiproliferative activity against human MCF7 cells after 72 hrs by SRB assay
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[PMID: 20178321] |
Chemical Information
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CAS No. 24044-52-8
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Masse moléculaire 250.23
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Formule C10H6N2O4S
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SMILES
O=C(N1)/C(SC1=O)=C/C2=CC([N+]([O-])=O)=CC=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DCAF11 ligand 2 Related Classifications
HY-W288798 Related Classifications
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