DCAF11 ligand 2
DCAF11 ligand 2 is an E3 ligase ligand that can be used in the recruitment of DCAF11. DCAF11 ligand 2 can be connected to the BRD4 ligand (HY-78695) by a linker to synthesis of PROTAC BRD4 degrader LGF308 (HY-181756).
For research use only. We do not sell to patients.
- CAS No.: 24044-52-8
- Formula: C10H6N2O4S
- Molecular Weight:250.23
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
DCAF11 |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MCF7 | IC50 |
55.8 μM
Compound: 11a(E)
|
Antiproliferative activity against human MCF7 cells after 72 hrs by SRB assay
Antiproliferative activity against human MCF7 cells after 72 hrs by SRB assay
|
[PMID: 20178321] |
Chemical Information
-
CAS No. 24044-52-8
-
Molecular Weight 250.23
-
Formula C10H6N2O4S
-
SMILES
O=C(N1)/C(SC1=O)=C/C2=CC([N+]([O-])=O)=CC=C2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)