SEPTIN3 - septin 3 Gene
Also Known as SEP3; SEPT3; bK250D10.3
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 55964
Summary
This gene belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, May 2018]
Biased expression in brain (RPKM 64.7) and placenta (RPKM 2.6).
SEPTIN3 Products (15)
| mRNA | Protein | Name |
|---|---|---|
| NM_001363845.2 | NP_001350774.1 | neuronal-specific septin-3 isoform C |
| NM_001389668.1 | NP_001376597.1 | neuronal-specific septin-3 isoform D |
| NM_001389669.1 | NP_001376598.1 | neuronal-specific septin-3 isoform E |
| NM_001389670.1 | NP_001376599.1 | neuronal-specific septin-3 isoform F |
| NM_001389671.1 | NP_001376600.1 | neuronal-specific septin-3 isoform G |
| NM_001389672.1 | NP_001376601.1 | neuronal-specific septin-3 isoform H |
| NM_001389673.1 | NP_001376602.1 | neuronal-specific septin-3 isoform I |
| NM_001389674.1 | NP_001376603.1 | neuronal-specific septin-3 isoform J |
| NM_001389675.1 | NP_001376604.1 | neuronal-specific septin-3 isoform K |
| NM_001389676.1 | NP_001376605.1 | neuronal-specific septin-3 isoform L |
| NM_001389677.1 | NP_001376606.1 | neuronal-specific septin-3 isoform M |
| NM_001389678.1 | NP_001376607.1 | neuronal-specific septin-3 isoform N |
| NM_001389679.1 | NP_001376608.1 | neuronal-specific septin-3 isoform O |
| NM_019106.6 | NP_061979.3 | neuronal-specific septin-3 isoform B |
| NM_145733.3 | NP_663786.2 | neuronal-specific septin-3 isoform A |
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SEPTIN3 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
SEPTIN3 | Q9UH03 | RNF4 | Homo sapiens | P78317 | 32296183 | |
|
Intra
|
SEPTIN3 | Q9UH03 | RNF4 | Homo sapiens | P78317 | 32296183 | |
|
Intra
|
SEPTIN3 | Q9UH03 | MAP1LC3B | Homo sapiens | Q9GZQ8 | 35932293 | |
|
Intra
|
SEPTIN3 | Q9UH03 | MAP1LC3B | Homo sapiens | Q9GZQ8 | 35932293 | |
|
Intra
|
SEPTIN3 | Q9UH03 | MAP1LC3B | Homo sapiens | Q9GZQ8 | 35932293 | |
|
Intra
|
SEPTIN3 | Q9UH03 | RNF8 | Homo sapiens | O76064 | 25416956 | |
|
Intra
|
SEPTIN3 | Q9UH03 | RNF8 | Homo sapiens | O76064 | 31515488 | |
|
Intra
|
SEPTIN3 | Q9UH03 | CKS1B | Homo sapiens | P61024 | 25416956 | |
|
Intra
|
SEPTIN3 | Q9UH03 | CKS1B | Homo sapiens | P61024 | 25416956 | |
|
Intra
|
SEPTIN3 | Q9UH03 | SEPTIN1 | Homo sapiens | Q8WYJ6 | 32296183 | |
|
Intra
|
SEPTIN3 | Q9UH03 | GABARAPL2 | Homo sapiens | P60520 | 35932293 | |
|
Intra
|
SEPTIN3 | Q9UH03 | GABARAPL2 | Homo sapiens | P60520 | 35932293 | |
|
Intra
|
SEPTIN3 | Q9UH03 | SDCBP | Homo sapiens | O00560 | 25416956 | |
|
Intra
|
SEPTIN3 | Q9UH03 | SEPTIN6 | Homo sapiens | Q14141 | 33961781 | |
|
Intra
|
SEPTIN3 | Q9UH03 | SEPTIN6 | Homo sapiens | Q14141 | 25416956 | |
|
Intra
|
SEPTIN3 | Q9UH03 | NTAQ1 | Homo sapiens | Q96HA8 | 25416956 | |
|
Intra
|
SEPTIN3 | Q9UH03 | NTAQ1 | Homo sapiens | Q96HA8 | 25416956 | |
|
Intra
|
SEPTIN3 | Q9UH03 | DDIT4L | Homo sapiens | Q96D03 | 32296183 | |
|
Intra
|
SEPTIN3 | Q9UH03 | DDIT4L | Homo sapiens | Q96D03 | 32296183 | |
|
Intra
|
SEPTIN3 | Q9UH03 | LASP1 | Homo sapiens | Q14847 | 25416956 | |
|
Intra
|
SEPTIN3 | Q9UH03 | LASP1 | Homo sapiens | Q14847 | 25416956 | |
|
Intra
|
SEPTIN3 | Q9UH03 | MOB1A | Homo sapiens | Q9H8S9 | 25416956 | |
|
Intra
|
SEPTIN3 | Q9UH03 | MOB1A | Homo sapiens | Q9H8S9 | 25416956 | |
|
Intra
|
SEPTIN3 | Q9UH03 | MOB1A | Homo sapiens | Q9H8S9 | 25416956 |
Cross: Cross-species interaction
Intra: Intraspecies interaction