2. Gene
  3. RPRD1B - regulation of nuclear pre-mRNA domain containing 1B Gene

RPRD1B - regulation of nuclear pre-mRNA domain containing 1B Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as K-H; CREPT; NET60; C20orf77; Kub5-Hera; dJ1057B20.2

Gene ID: 58490 | Gene type: protein coding

About RPRD1B

Cytogenetic location: 20q11.23 Genomic coordinates (GRCh38): 20:38,033,746-38,092,364 (from NCBI)

This gene has 9 transcripts (splice variants), 136 orthologues and 2 paralogues. Ubiquitous expression in bone marrow (RPKM 7.4), lymph node (RPKM 7.2) and 25 other tissues.

Summary

Enables RNA polymerase II complex binding activity and identical protein binding activity. Involved in positive regulation of cell population proliferation; regulation of cell cycle process; and regulation of transcription by RNA polymerase II. Located in nucleoplasm. Part of RNA polymerase II, holoenzyme. [provided by Alliance of Genome Resources, Apr 2022]

RPRD1B Products(1)

mRNA Protein Name
NM_021215.4 NP_067038.1 regulation of nuclear pre-mRNA domain-containing protein 1B

RPRD1B Protein Structure

CTD_bind

CTD_bind: RNA polymerase II-binding domain. (56 - 117)

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  • 326 a.a.
Protein Preferred Names Protein Names

regulation of nuclear pre-mRNA domain-containing protein 1B

Ku70-binding protein 5-Hera

Recombinant RPRD1B Proteins

Cat. No. Product Name Accession Purity
HY-P77184 RPRD1B Protein, Human (HEK293, His) Q9NQG5 (M1-D326) ≥95%

Related Diseases

Diseases Alias
Polyneuropathy Due To Drug
Retroperitoneal Leiomyosarcoma
Inflammatory And Toxic Neuropathy
Retroperitoneal Sarcoma
Atrial Tachyarrhythmia With Short Pr Interval

Lown-Ganong-Levine Syndrome

Syndrome Of Short P-R Interval, Normal Qrs Complexes, And Supraventricular Tachycardias

Lgl Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12217 RPRD1B Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus RPRD1B VGNC VGNC:34127
Canis familiaris RPRD1B VGNC VGNC:45727
Felis catus RPRD1B VGNC VGNC:64749
Macaca mulatta RPRD1B VGNC VGNC:77024
Mus musculus RPRD1B MGD MGI:1917720
Rattus norvegicus RPRD1B RGD RGD:1304782
Others RPRD1B NCBI