country

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-101367

Copy Link Print Information

GR 55562

GR 55562 is a selective 5-HT_1B receptor antagonist. GR 55562 can be used for the research of nerve disease.

For research use only. We do not sell to patients.

CAS No.: 159533-26-3
Formula: C₂₃H₂₅N₃O₂
Molecular Weight:375.46

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

GR 55562 Chemical Structure

CAS No.: 159533-26-3

Size

Price

Stock

Quantity

Sample (0.1mg)

In-stock

(In Japan)

Apply Now

Get Quote Ask For Quote & Lead Time Consult sales personnel for more information Check price and availability Get Quote Ask For Quote & Lead Time Consult sales personnel for more information Check price and availability

Bulk Inquiry

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

GR 55562 is a selective 5-HT_1B receptor antagonist. GR 55562 can be used for the research of nerve disease^[1].

IC₅₀ & Target^[1]

5-HT_1B Receptor

All 5-HT Receptor Isoforms :

In Vivo

GR 55562 (0.1-10 μg/side) into accumbens subregions does not evoke cocaine-lever responding^[1].
GR 55562 (0.1-10 μg/side) in the accumbens shell or core failed to modulate the discriminative stimulus effects of cocaine (5 mg/kg)^[1].
GR 55562 (1 μg/side) significantly attenuates the enhancement of cocaine discrimination^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 159533-26-3
Molecular Weight 375.46
Formula C₂₃H₂₅N₃O₂
SMILES

O=C(NC1=CC=C(C2=CC=NC=C2)C=C1)C3=CC=C(O)C(CCCN(C)C)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Filip M, et al. Effects of serotonin (5-HT)(1B) receptor ligands, microinjected into accumbens subregions, on cocaine discrimination in rats. Naunyn Schmiedebergs Arch Pharmacol. 2002;366(3):226-234. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

Get Quote In-stock