2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. GR 55562

GR 55562 is a selective 5-HT1B receptor antagonist. GR 55562 can be used for the research of nerve disease.

For research use only. We do not sell to patients.

GR 55562

GR 55562 Chemical Structure

CAS No. : 159533-26-3

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GR 55562 Related Antibodies

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Description

GR 55562 is a selective 5-HT1B receptor antagonist. GR 55562 can be used for the research of nerve disease[1].

IC50 & Target[1]

5-HT1B Receptor

 

In Vivo

GR 55562 (0.1-10 μg/side) into accumbens subregions does not evoke cocaine-lever responding[1].
GR 55562 (0.1-10 μg/side) in the accumbens shell or core failed to modulate the discriminative stimulus effects of cocaine (5 mg/kg)[1].
GR 55562 (1 μg/side) significantly attenuates the enhancement of cocaine discrimination[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

375.46

Formula

C23H25N3O2
CAS No.
SMILES

O=C(NC1=CC=C(C2=CC=NC=C2)C=C1)C3=CC=C(O)C(CCCN(C)C)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GR 55562 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GR 55562159533-26-3GR55562GR-555625-HT ReceptorSerotonin Receptor5-hydroxytryptamine Receptorserotonin (5-HT)antagonist5-HT1B receptorInhibitorinhibitorinhibit

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