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Cat. No.: HY-101367

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GR 55562

GR 55562 is a selective 5-HT_1B receptor antagonist. GR 55562 can be used for the research of nerve disease.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 159533-26-3
Formule: C₂₃H₂₅N₃O₂
Masse moléculaire:375.46

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

GR 55562 Chemical Structure

CAS No.: 159533-26-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Bioz

Activité biologique

Description

GR 55562 is a selective 5-HT_1B receptor antagonist. GR 55562 can be used for the research of nerve disease^[1].

IC₅₀ & Target^[1]

5-HT_1B Receptor

Voir tous les produits spécifiques à Isoform 5-HT Receptor :

In Vivo

GR 55562 (0.1-10 μg/side) into accumbens subregions does not evoke cocaine-lever responding^[1].
GR 55562 (0.1-10 μg/side) in the accumbens shell or core failed to modulate the discriminative stimulus effects of cocaine (5 mg/kg)^[1].
GR 55562 (1 μg/side) significantly attenuates the enhancement of cocaine discrimination^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 159533-26-3
Masse moléculaire 375.46
Formule C₂₃H₂₅N₃O₂
SMILES

O=C(NC1=CC=C(C2=CC=NC=C2)C=C1)C3=CC=C(O)C(CCCN(C)C)=C3
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Filip M, et al. Effects of serotonin (5-HT)(1B) receptor ligands, microinjected into accumbens subregions, on cocaine discrimination in rats. Naunyn Schmiedebergs Arch Pharmacol. 2002;366(3):226-234. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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