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GSK-1070806

(Synonyms: Aletekitug)
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Based on 1 Customer Validation

GSK-1070806 (Aletekitug) is a humanized IgG1/κ monoclonal antibody targeting IL-18. GSK-1070806 neutralizes IL-18 activity.GSK-1070806 can be used for the research of inflammation. The isotype control for GSK-1070806 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

For research use only. We do not sell to patients.

  • Purity: 99.84%
  • Molecular Weight:147.38 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for GSK-1070806
  • Experimental Validation Results for GSK-1070806
  • Experimental Validation Results for GSK-1070806
  • GSK-1070806 Chemical Structure
    GSK-1070806 Chemical Structure
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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GSK-1070806 Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Use of MCE Products

All Interleukin Related Isoforms

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100 mg

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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized IL-18 Protein, Human can bind GSK-1070806. The EC50 for this effect is 10.16 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 A431 cells with GSK-1070806 (HY-P990591, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • GSK-1070806 Chemical Structure
    1/16
  • GSK-1070806
  • Immobilized IL-18 Protein, Human can bind GSK-1070806. The EC50 for this effect is 10.16 ng/mL.
  • Flow cytometric analysis of 1X106 A431 cells with GSK-1070806 (HY-P990591, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).