GW0072
GW0072 is a partial agonist of PPARγ and does not directly bind to the AF-2 helix of PPARγ, resulting in specific partial receptor transcriptional activation properties.
For research use only. We do not sell to patients.
- CAS No.: 321557-86-2
- Formula: C37H46N2O4S
- Molecular Weight:614.84
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 321557-86-2
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Molecular Weight 614.84
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Formula C37H46N2O4S
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SMILES
O=C(C1=CC=C(C=C1)CCCCN2[C@@H](S[C@H](C2=O)CC(N(CC3=CC=CC=C3)CC4=CC=CC=C4)=O)CCCCCCC)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Ligand entry pathways in the ligand binding domain of PPARc receptor
[2]. Genest D, et al. Ligand-escape pathways from the ligand-binding domain of PPARgamma receptor as probed by molecular dynamics simulations. Eur Biophys J. 2008 Apr;37(4):369-79. [Content Brief]
[3]. Zhang F, et al. Selective Modulators of PPAR-gamma Activity: Molecular Aspects Related to Obesity and Side-Effects. PPAR Res. 2007;2007:32696. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GW0072 Related Classifications
HY-118097 Related Classifications
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