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H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycystic kidney disease and is used in autosomal dominant polycystic kidney disease research.

For research use only. We do not sell to patients.

H2-Gamendazole Chemical Structure

H2-Gamendazole Chemical Structure

CAS No. : 877768-84-8

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1 mg USD 145 In-stock
5 mg USD 440 In-stock
10 mg USD 660 In-stock
25 mg USD 1150 In-stock
50 mg USD 1750 In-stock
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Based on 1 publication(s) in Google Scholar

H2-Gamendazole Related Antibodies

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Description

H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycystic kidney disease and is used in autosomal dominant polycystic kidney disease research[1].

Molecular Weight

417.21

Formula

C18H13Cl2F3N2O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(CCC1=NN(CC2=CC=C(C=C2Cl)Cl)C3=C1C=CC(C(F)(F)F)=C3)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (299.61 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3969 mL 11.9844 mL 23.9687 mL
5 mM 0.4794 mL 2.3969 mL 4.7937 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3969 mL 11.9844 mL 23.9687 mL 59.9219 mL
5 mM 0.4794 mL 2.3969 mL 4.7937 mL 11.9844 mL
10 mM 0.2397 mL 1.1984 mL 2.3969 mL 5.9922 mL
15 mM 0.1598 mL 0.7990 mL 1.5979 mL 3.9948 mL
20 mM 0.1198 mL 0.5992 mL 1.1984 mL 2.9961 mL
25 mM 0.0959 mL 0.4794 mL 0.9587 mL 2.3969 mL
30 mM 0.0799 mL 0.3995 mL 0.7990 mL 1.9974 mL
40 mM 0.0599 mL 0.2996 mL 0.5992 mL 1.4980 mL
50 mM 0.0479 mL 0.2397 mL 0.4794 mL 1.1984 mL
60 mM 0.0399 mL 0.1997 mL 0.3995 mL 0.9987 mL
80 mM 0.0300 mL 0.1498 mL 0.2996 mL 0.7490 mL
100 mM 0.0240 mL 0.1198 mL 0.2397 mL 0.5992 mL
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H2-Gamendazole Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

H2-Gamendazole877768-84-8OthersInhibitorinhibitorinhibit

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