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Cat. No.: HY-151633

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hCAIX-IN-14

hCAIX-IN-14 (compound 5a) is a potent inhibitor of human CA IX with a K_i value of 134.8 nM.

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CAS No.: 77113-78-1
Formule: C₁₁H₁₇ClN₆O₂S
Masse moléculaire:332.81

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

hCAIX-IN-14 Chemical Structure

CAS No.: 77113-78-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Chemical Information
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Description

hCAIX-IN-14 (compound 5a) is a potent inhibitor of human CA IX with a K_i value of 134.8 nM^[1].

IC₅₀ & Target

^[1]

hCA IX

134.8 nM (Ki)

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Chemical Information

CAS No. 77113-78-1
Masse moléculaire 332.81
Formule C₁₁H₁₇ClN₆O₂S
SMILES

O=S(C1=CC=C(N2C(C)(C)N=C(N)N=C2N)C=C1)(N)=O.Cl
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Zain-Alabdeen AI, et al. Synthesis and anticancer activity of new benzensulfonamides incorporating s-triazines as cyclic linkers for inhibition of carbonic anhydrase IX. Sci Rep. 2022 Oct 6;12(1):16756. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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hCAIX-IN-14

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Activité biologique

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IC50 & Target

Chemical Information

Pureté et documentation

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Help & FAQs

hCAIX-IN-14 Related Classifications

HY-151633 Related Classifications

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