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Cat. No.: HY-177875

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Hsp90-IN-44

Hsp90-IN-44 (compound 16) is a Hsp90 inhibitor with an IC₅₀ of 9.8 µM. Hsp90-IN-44 can be used for cancer research.

For research use only. We do not sell to patients.

CAS No.: 934346-12-0
Formula: C₁₉H₁₆FN₅O₂
Molecular Weight:365.36

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Hsp90-IN-44 Chemical Structure

CAS No.: 934346-12-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Hsp90-IN-44 (compound 16) is a Hsp90 inhibitor with an IC₅₀ of 9.8 µM. Hsp90-IN-44 can be used for cancer research^[1].

IC₅₀ & Target^[1]

HSP90

9.8 μM (IC₅₀)

All HSP Isoforms :

Chemical Information

CAS No. 934346-12-0
Molecular Weight 365.36
Formula C₁₉H₁₆FN₅O₂
SMILES

O=C1N[C@@H](C2=C(C(N3)=CC=CC3=O)C=C(C=C2)F)CC4=NC(N)=NC(C)=C41
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. McBride CM, et al. Design, structure-activity relationship, and in vivo characterization of the development candidate NVP-HSP990. J Med Chem. 2014 Nov 13;57(21):9124-9. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Hsp90-IN-44

All HSP Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Hsp90-IN-44 Related Classifications

HY-177875 Related Classifications