DA-023
Based on 1 Customer Validation
DA-023 (Compound 4) is a selective positive allosteric modulator (PAM) of EAAT2 with an EC50 value of 1 nM.
For research use only. We do not sell to patients.
- Purity: 98.01%
- CAS No.: 2585643-97-4
- Formula: C20H25N7
- Molecular Weight:363.46
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Chemical Information
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CAS No. 2585643-97-4
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Appearance Solid
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Molecular Weight 363.46
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Formula C20H25N7
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Color White to off-white
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SMILES
CN1CCN(C(C2=NN=NN2CCC3=CC=CC=C3)C4=CC=CN=C4)CC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL (275.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7513 mL | 13.7567 mL | 27.5133 mL | 68.7834 mL |
| 5 mM | 0.5503 mL | 2.7513 mL | 5.5027 mL | 13.7567 mL | |
| 10 mM | 0.2751 mL | 1.3757 mL | 2.7513 mL | 6.8783 mL | |
| 15 mM | 0.1834 mL | 0.9171 mL | 1.8342 mL | 4.5856 mL | |
| 20 mM | 0.1376 mL | 0.6878 mL | 1.3757 mL | 3.4392 mL | |
| 25 mM | 0.1101 mL | 0.5503 mL | 1.1005 mL | 2.7513 mL | |
| 30 mM | 0.0917 mL | 0.4586 mL | 0.9171 mL | 2.2928 mL | |
| 40 mM | 0.0688 mL | 0.3439 mL | 0.6878 mL | 1.7196 mL | |
| 50 mM | 0.0550 mL | 0.2751 mL | 0.5503 mL | 1.3757 mL | |
| 60 mM | 0.0459 mL | 0.2293 mL | 0.4586 mL | 1.1464 mL | |
| 80 mM | 0.0344 mL | 0.1720 mL | 0.3439 mL | 0.8598 mL | |
| 100 mM | 0.0275 mL | 0.1376 mL | 0.2751 mL | 0.6878 mL |