Halometasone
Based on 1 Customer Validation
Halometasone is a corticosteroid compound that can reduce the expression of serum leukotriene B4 (LTB4) and thymic stromal lymphopoietin (TSLP). Halometasone can be used in research on psoriasis and eczematous skin diseases.
For research use only. We do not sell to patients.
- CAS No.: 50629-82-8
- Formula: C22H27ClF2O5
- Molecular Weight:444.90
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Leukotriene Receptor Isoforms
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Biological Activity
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LTB4 |
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 50629-82-8
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Appearance Solid
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Molecular Weight 444.90
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Formula C22H27ClF2O5
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Color White to off-white
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SMILES
F[C@@]12[C@](C[C@@H](C([C@@]2(C=C3Cl)C)=CC3=O)F)([H])[C@@]4([H])[C@](C[C@@H]1O)([C@](O)([C@@H](C4)C)C(CO)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (272 KB)
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SDS (557 KB)
- English - EN (557 KB)
- Français - FR (557 KB)
- Deutsch - DE (557 KB)
- Norwegian - NO (557 KB)
- Español - ES (557 KB)
- Swedish - SV (557 KB)
- Italian - IT (557 KB)
- Korean - KR (557 KB)
- Portuguese - PT (557 KB)
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Handling Instructions (2659 KB)
References
[1]. Zhu J W, et al. Role of VEGF receptors in normal and psoriatic human keratinocytes: evidence from irradiation with different UV sources[J]. PLoS One, 2013, 8(1): e55463. [Content Brief]
[2]. Cao J, et al. Effect of halometasone cream combined with Simiao pill on the therapeutic effect and expression of serum leukotriene B4 (LTB4) and thymic stromal lymphopoietin (TSLP) in patients with eczema, and the factors influencing its clinical efficacy. Ann Palliat Med. 2021 Nov;10(11):11643-11652. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)